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利用行政数据识别安大略省的2型糖尿病患者:两种病例定义的比较。

Identifying Ontarians with Type 2 Diabetes Mellitus in Administrative Data: A Comparison of Two Case Definitions.

作者信息

Houlden Robyn L, Thayalan Nilasha, Shi Scott, Kukaswadia Atif, Mau Godfrey, Liu Aiden

机构信息

Division of Endocrinology, Queen's University, Kingston, ON, Canada.

IQVIA Solutions Canada Inc, Mississauga, ON, Canada.

出版信息

Diabetes Ther. 2024 Mar;15(3):677-689. doi: 10.1007/s13300-024-01535-4. Epub 2024 Feb 10.

Abstract

INTRODUCTION

This study compared two previously validated sensitive and specific diabetes case definitions to explore the impact of different classification methods in Ontario ICES administrative data.

METHODS

This study included patients captured by the Ontario Diabetes Database with type 2 diabetes using either the sensitive cohort definition (≥ 2 physician visits for diabetes within 1 year or ≥ 1 drug claim for diabetes or ≥ 1 hospitalization with diabetes), or the specific cohort definition (≥ 3 physician visits for diabetes within 1 year), between October 1, 2013 to September 30, 2015. Each cohort's demographic and clinical features were described using descriptive analysis.

RESULTS

Using sensitive and specific definitions, 1,093,812 and 783,228 patients with type 2 diabetes were identified, respectively. Overall, the demographic and clinical characteristics were similar between cohorts. Patients in the sensitive cohort had mean age of 64.1 years and were 52.4% male, compared to 64.8 years and 53.6% male in the specific cohort. In the sensitive and specific cohorts respectively, 64.4% and 55.7% of patients reported one-year mean HbA1c of < 7% (53 mmol/mol) and 25.3% and 31.5% reported levels between 7.0-8.5% (53-69 mmol/mol).

CONCLUSIONS

Although sample sizes were different between sensitive and specific cohorts, demographic and clinical characteristics were similar.

摘要

引言

本研究比较了两种先前经验证的敏感且特异的糖尿病病例定义,以探讨安大略省ICES行政数据中不同分类方法的影响。

方法

本研究纳入了2013年10月1日至2015年9月30日期间安大略糖尿病数据库中使用敏感队列定义(1年内≥2次糖尿病医生就诊或≥1次糖尿病药物报销或≥1次糖尿病住院治疗)或特异队列定义(1年内≥3次糖尿病医生就诊)确诊的2型糖尿病患者。采用描述性分析描述每个队列的人口统计学和临床特征。

结果

分别使用敏感定义和特异定义,共识别出1,093,812例和783,228例2型糖尿病患者。总体而言,各队列的人口统计学和临床特征相似。敏感队列患者的平均年龄为64.1岁,男性占52.4%,而特异队列患者的平均年龄为64.8岁,男性占53.6%。在敏感队列和特异队列中,分别有64.4%和55.7%的患者报告1年平均糖化血红蛋白<7%(53 mmol/mol),25.3%和31.5%的患者报告糖化血红蛋白水平在7.0 - 8.5%(53 - 69 mmol/mol)之间。

结论

尽管敏感队列和特异队列的样本量不同,但人口统计学和临床特征相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf1c/10942959/401903ace48c/13300_2024_1535_Fig1_HTML.jpg

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