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伴有难治性中间神经痛和同侧突发性中枢性面瘫及感音神经性听力损失病史患者的中间神经萎缩:尸体临床图像和手术视频。

Unusual Atrophic Nervus Intermedius in a Patient with Refractory Nervus Intermedius Neuralgia and History of Ipsilateral Sudden-Onset Central Facial Palsy and Sensorineural Hearing Loss: Cadaveric-Clinical Images with Surgical Video.

机构信息

Department of Neurosurgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.

Department of Neurosurgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.

出版信息

World Neurosurg. 2024 May;185:91-94. doi: 10.1016/j.wneu.2024.02.026. Epub 2024 Feb 8.

DOI:10.1016/j.wneu.2024.02.026
PMID:38340797
Abstract

Nervus intermedius (NI) arises from the superior salivary nucleus, solitary nucleus, and trigeminal tract. It leaves the pons as 1 to 5 roots and travels between the facial and vestibulocochlear nerves before merging with the facial nerve within the internal auditory canal. The mastoid segment of the facial nerve then gives rise to a sensory branch that supplies the posteroinferior wall of the external auditory meatus and inferior pina. This complex pathway renders the nerve susceptible to various pathologies, leading to NI neuralgia. Here, the authors present an unusual intraoperative finding of an atrophic NI in a patient with refractory NI neuralgia and a history of ipsilateral sudden-onset central facial palsy and microvascular decompression for trigeminal neuralgia. The patient underwent NI sectioning via the previous retrosigmoid window and achieved partial ear pain improvement. The gross size of the NI is compared with a cadaveric specimen through stepwise dissection. This case highlights the potential significance of subtle central ischemic events and subsequent atrophy of NI in the pathogenesis of NI neuralgia, as well as the ongoing need to investigate the therapeutic efficacy of nerve sectioning.

摘要

中间神经(NI)起源于上涎核、孤束核和三叉神经脊束。它从脑桥离开,形成 1 到 5 根神经根,在与面神经合并进入内听道之前,穿行于面神经和前庭耳蜗神经之间。面神经的乳突段然后产生一个感觉支,供应外耳道后下壁和下棘。这条复杂的通路使神经容易受到各种病理的影响,导致 NI 神经痛。在这里,作者报告了一例罕见的术中发现,一名难治性 NI 神经痛患者,有同侧突发性中枢性面瘫和三叉神经痛微血管减压术病史。患者通过先前的乙状窦后窗接受了 NI 切断术,部分改善了耳部疼痛。通过逐步解剖,将 NI 的大体大小与尸体标本进行了比较。该病例强调了中枢性缺血性事件和随后的 NI 萎缩在 NI 神经痛发病机制中的潜在意义,以及需要继续研究神经切断术的治疗效果。

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Unusual Atrophic Nervus Intermedius in a Patient with Refractory Nervus Intermedius Neuralgia and History of Ipsilateral Sudden-Onset Central Facial Palsy and Sensorineural Hearing Loss: Cadaveric-Clinical Images with Surgical Video.伴有难治性中间神经痛和同侧突发性中枢性面瘫及感音神经性听力损失病史患者的中间神经萎缩:尸体临床图像和手术视频。
World Neurosurg. 2024 May;185:91-94. doi: 10.1016/j.wneu.2024.02.026. Epub 2024 Feb 8.
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Pain-free and pain-controlled survival after sectioning the nervus intermedius in nervus intermedius neuralgia: a single-institution review.神经节段性中间神经切断术治疗中间神经痛:单中心回顾性研究。
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