Beijing Anzhen Hospital, Capital Medical University, 2 Anzhen Road, Chaoyang District, Beijing, 100029, China.
Capital Institute of Pediatrics, 2 Yabao Road, Chaoyang District, Beijing, 100045, China.
Eur Arch Otorhinolaryngol. 2024 Jul;281(7):3615-3623. doi: 10.1007/s00405-024-08505-3. Epub 2024 Feb 11.
Chronic rhinosinusitis (CRS) is a common disease that affects patients' quality of life (QoL). We aim to explore which symptoms bothered the patient most.
This is a cross-sectional study of CRS patients 2 years after endoscopic sinus surgery (ESS). The main observation indicators were SNOT-22 and visual analog scale (VAS) scores. The patients were grouped according to clinical control standard of EPOS 2020. Patients' symptom scores and postoperative medication were used for analysis.
A total of 276 patients were included, among them, uncontrolled patients accounted for 23.9%, sense of taste/smell, fatigue, lacking of a good night's sleep, reduced concentration and reduced productivity were the most serious symptoms that troubled them. VAS and SNOT-22 scores were significantly different among all groups (P = 0.000), and had clinical significance for the diagnosis of clinical uncontrolled patients (both P < 0.0001). Furthermore, the duration of corticosteroids use and nasal saline irrigation in uncontrolled patients was significantly longer than that in other patients (P < 0.05).
There are significant differences in the QoL of CRS patients with different clinical control, sleep and psychological disorders are main symptoms that affect the QoL of CRS patients, and more targeted management of sleep/psychological issues may be needed especially for uncontrolled patients.
慢性鼻-鼻窦炎（CRS）是一种常见疾病，影响患者的生活质量（QoL）。本研究旨在探讨哪种症状最困扰患者。
这是一项内镜鼻窦手术（ESS）后 2 年的 CRS 患者的横断面研究。主要观察指标为 SNOT-22 和视觉模拟量表（VAS）评分。根据 EPOS 2020 的临床控制标准对患者进行分组。分析患者的症状评分和术后用药情况。
共纳入 276 例患者，其中未控制患者占 23.9%，味觉/嗅觉丧失、疲劳、睡眠不佳、注意力和工作效率下降是困扰他们最严重的症状。所有组之间的 VAS 和 SNOT-22 评分均有显著差异（P=0.000），对临床未控制患者的诊断具有临床意义（均 P<0.0001）。此外，未控制患者的皮质激素使用时间和鼻腔盐水冲洗时间明显长于其他患者（P<0.05）。
不同临床控制患者的生活质量存在显著差异，睡眠和心理障碍是影响 CRS 患者生活质量的主要症状，对未控制患者可能需要进行更有针对性的睡眠/心理问题管理。
