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分散在氧化石墨烯上的SrTiO纳米颗粒的片状结构:一种用于测定牛奶和蜂蜜样品中氯霉素的选择性和灵敏电化学传感器。

Flake-like structure of SrTiO nanoparticles dispersed on graphene oxide: A selective and sensitive electrochemical sensor for determination of chloramphenicol in milk and honey samples.

作者信息

Sakaleshpur Kumar Gagankumar, Ballur Prasanna Sanjay, Lokesh Marenahalli Bhuvan, Shadakshari Sandeep, Arehalli Shivamurthy Santhosh, Rajabathar Jothi Ramalingam, Chimatahalli Shanthakumar Karthik, Han Young-Kyu

机构信息

Department of Chemistry, SJCE, JSS Science and Technology University, Karnataka 570006, India; Department of Energy and Materials Engineering, Dongguk University-Seoul, Seoul 100-715, Republic of Korea.

Department of Chemical Engineering and Biotechnology, National Taipei University of Technology (Taipei Tech), Taipei 10608, Taiwan.

出版信息

Food Chem. 2024 Jun 30;444:138637. doi: 10.1016/j.foodchem.2024.138637. Epub 2024 Feb 8.

Abstract

The use of Chloramphenicol (CAP), a potent antibiotic with broad-spectrum capabilities in food-producing animals has been restricted by the European Union and several other countries due to its severe side effects. Thus, CAP must be detected quickly and sensitively. In this investigation, the preparation of SrTiO nanoparticles was carried out utilizing a hydrothermal technique. The as-synthesized strontium titanate was decorated on the graphene oxide (SrTiO/GO) using an ultrasonication method. An electrochemical sensor was developed by employing a modified electrode consisting of SrTiO/GO, which can accurately detect CAP in food samples. The synergistic effect of SrTiO and GO could improve the peak current response. Remarkably, the SrTiO/GO-modified glassy carbon electrode has a LOD and sensitivity of 6.08 µM nM and 2.771 µA·μM·cm, respectively. This modified electrode was evaluated in food samples and had an outstanding reaction with a high percentage of recovery, which makes it a potential electrocatalyst for CAP detection.

摘要

氯霉素(CAP)是一种在食用动物中具有广谱抗菌能力的强效抗生素,由于其严重的副作用,已被欧盟和其他几个国家限制使用。因此,必须快速、灵敏地检测CAP。在本研究中,采用水热法制备了钛酸锶纳米颗粒。通过超声法将合成的钛酸锶修饰在氧化石墨烯(SrTiO/GO)上。采用由SrTiO/GO组成的修饰电极开发了一种电化学传感器,该传感器能够准确检测食品样品中的CAP。SrTiO和GO的协同作用可以改善峰值电流响应。值得注意的是,SrTiO/GO修饰玻碳电极的检测限和灵敏度分别为6.08 nM和2.771 μA·μM·cm²。该修饰电极在食品样品中进行了评估,具有出色的反应和高回收率,这使其成为检测CAP的潜在电催化剂。

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