Thomas J, Castaing D, Thomas E, Miramand J L, Gaultier J, Maistre-Charransol G, Barthelemy C, Legrand J C
Magnesium. 1985;4(5-6):316-8.
Rats with a portacaval anastomosis are known to be susceptible to develop uric acid stones. The present studies were undertaken to investigate urinary Mg, Ca and oxalate excretion in such rats. We found that their Mg excretion was doubled, Ca excretion tripled, and oxaluria somewhat decreased. The Ca crystallization attributed to the increased Ca2+ in the urine is, therefore, somewhat held in check by the increased presence of Mg in the urine and by decreased oxalates.
已知患有门腔静脉吻合术的大鼠易患尿酸结石。本研究旨在调查此类大鼠的尿镁、钙和草酸盐排泄情况。我们发现它们的镁排泄量增加了一倍,钙排泄量增加了两倍,而草酸盐尿症有所减少。因此,尿液中钙结晶的增加归因于尿液中Ca2+的增加,在一定程度上受到尿液中镁含量增加和草酸盐减少的抑制。