Pupek-Musialik D, Głuszek J
Kliniki Nadciśnienia Tetniczego Instytuty Kardiologii AM im. K. Marcinkowskiego w Poznaniu.
Pol Tyg Lek. 1991;46(4-5):74-5.
The study involved 30 patients treated with nifedipine in daily dose of 30 mg for 7 days. Calcium, magnesium, phosphate, oxalate, and uric acid levels in the urine were measured. It was found that nifedipine significantly decreased oxaluria urinary excretion of calcium, magnesium, phosphate, and uric acid remained unchanged following nifedipine therapy. Results may suggest that nifedipine may exert an influence on renal stone formation.
该研究纳入了30例患者，给予硝苯地平每日剂量30mg，治疗7天。测量了尿液中的钙、镁、磷酸盐、草酸盐和尿酸水平。结果发现，硝苯地平显著降低了草酸盐尿，硝苯地平治疗后钙、镁、磷酸盐和尿酸的尿排泄量保持不变。结果可能提示硝苯地平可能对肾结石形成产生影响。
