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伪装成急性横贯性脊髓炎的产后低铜性脊髓病:一例报告及罕见表现的文献综述

Postpartum Hypocupric Myelopathy Masquerading as Acute Transverse Myelitis: A Case Report and Literature Review of a Rare Presentation.

作者信息

Pantbalekundri Nikhil, Kumar Sunil, Acharya Sourya, Bedi Gautam

机构信息

Department of General Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 Jan 12;16(1):e52149. doi: 10.7759/cureus.52149. eCollection 2024 Jan.

Abstract

The symptoms of transverse myelitis, an acute demyelinating inflammatory condition of the spinal cord, include motor, sensory, and bowel-bladder dysfunction that can develop suddenly or gradually. Several etiologies, such as bacterial, fungal, or viral infections, cancer, autoimmune diseases, vascular problems, and environmental variables, can cause it. The identification of copper deficiency myelopathy (CDM) as a curable cause of non-compressive inflammatory myelopathy has only occurred recently. Patients frequently present with sensory complaints and a spastic gait. The neurological disease may exist independently of the hematologic signs. Only a few cases of copper myelopathy in peripartum women have been documented. Given that hypocupric myelopathy is a treatable cause of debilitating paraplegia, maintaining clinical vigilance will be crucial in minimizing neurological sequelae, as demonstrated in this case report.

摘要

横贯性脊髓炎是脊髓的一种急性脱髓鞘性炎症性疾病,其症状包括运动、感觉及膀胱直肠功能障碍,这些症状可突然或逐渐出现。多种病因,如细菌、真菌或病毒感染、癌症、自身免疫性疾病、血管问题及环境因素等,均可导致该病。铜缺乏性脊髓病(CDM)作为非压迫性炎症性脊髓病的一种可治愈病因,直到最近才被发现。患者常表现出感觉异常及痉挛性步态。该神经疾病可能独立于血液学体征存在。围产期女性铜缺乏性脊髓病的病例记录仅有少数。鉴于低铜性脊髓病是导致使人衰弱的截瘫的一种可治疗病因,保持临床警惕对于将神经后遗症降至最低至关重要,本病例报告即证明了这一点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ec5/10858993/d16614bc760e/cureus-0016-00000052149-i01.jpg

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