Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Department of Nephrology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Saudi J Kidney Dis Transpl. 2023 Jul 1;34(4):371-377. doi: 10.4103/1319-2442.395454. Epub 2024 Feb 12.
Malakoplakia is an uncommon inflammatory disease that can involve many organ systems but is often encountered in the urogenital tract. Kidney allograft malakoplakia is even rarer and can have a diffuse parenchymal or a pseudotumoral presentation. We describe a case of grafi malakoplakia in an adult female, who presented with dull aching pain in the right loin, fever, and vomiting. Ultrasonography of the kidney graft showed a heterogeneous lesion (2.6 cm × 2.9 cm), raising suspicion of primary or metastatic renal tumors. The diagnosis was established after a histopathological examination of the kidney biopsy. This pseudotumoral presentation of malakoplakia can mimic renal cell carcinoma, lymphoma, fungal infections, or tuberculosis. It is essential to perform a biopsy for establishing the diagnosis.
黏膜相关样浆细胞瘤病是一种不常见的炎症性疾病,可累及多个器官系统,但常发生于泌尿生殖系统。肾移植后黏膜相关样浆细胞瘤病更罕见,可表现为弥漫性实质或假性肿瘤样。我们描述了 1 例成年女性肾移植后黏膜相关样浆细胞瘤病,其表现为右腰部隐痛、发热和呕吐。肾移植超声显示混杂性病变(2.6cm×2.9cm),提示原发性或转移性肾肿瘤。在肾活检的组织病理学检查后做出了诊断。黏膜相关样浆细胞瘤病的这种假性肿瘤样表现可模拟肾细胞癌、淋巴瘤、真菌感染或结核。为明确诊断,进行活检至关重要。