Osborn D E, Castro J E, Ansell I D
Hum Pathol. 1977 May;8(3):341-4. doi: 10.1016/s0046-8177(77)80031-2.
Malakoplakia is an uncommon chronic inflammatory disease characterized by histocytes with intracellular Michaelis-Gutmann bodies. The etiology is uncertain, but it is thought that depressed macrophage phagocytosis of bacteria is important. This presentation describes a case of malakoplakia arising in a cadaver renal transplant. The association of long term immunosuppression and repeated E. coli urinary tract infections is discussed.
软斑病是一种罕见的慢性炎症性疾病，其特征为组织细胞内含有米氏小体。病因尚不确定，但据认为巨噬细胞对细菌的吞噬功能降低很重要。本病例报告描述了一例尸体肾移植后发生的软斑病。文中讨论了长期免疫抑制与反复的大肠杆菌尿路感染之间的关联。
