Clinic for Cardio-Thoracic Surgery, Herz- und Diabeteszentrum Nordrhein-Westfalen, Bad Oeynhausen, Nordrhein-Westfalen, Germany.
Thorac Cardiovasc Surg. 2024 Dec;72(8):624-630. doi: 10.1055/a-2266-7677. Epub 2024 Feb 12.
Surgical mitral valve repair is the gold standard treatment of severe primary mitral regurgitation (MR). In the light of rapidly evolving percutaneous technologies, current surgical outcome data are essential to support heart-team-based decision-making.
This retrospective, high-volume, single-center study analyzed in 1779 patients with primary MR early morbidity and mortality, postoperative valve function, and long-term survival after mitral valve (MV) repair. Surgeries were performed between 2009 and 2022. Surgical approaches included full sternotomy (FS) and right-sided minithoracotomy (minimally invasive cardiac [MIC] surgery).
Of the surgeries (mean age: 59.9 [standard deviation:11.4] years; 71.5% males), 85.6% ( = 1,527) were minithoracotomies. Concomitant procedures were performed in 849 patients (47.7%), including tricuspid valve and/or atrial septal defect repair, cryoablation, and atrial appendage closure. The majority of patients did not need erythrocyte concentrates. Mediastinitis and rethoracotomy for bleeding rates were 0.1 and 4.3%, respectively. Reoperation before discharge for failed repair was necessary in 12 patients (0.7%). Freedom from more than moderate MR was > 99%. Thirty-day mortality was 0.2% and did not differ significantly between groups ( = 0.37). Median follow-up was 48.2 months with a completeness of 95.9%. Long-term survival was similar between groups ( = 0.21). In the FS and MIC groups, 1-, 5-, and 10-year survival rates were 98.8 and 98.8%, 92.9 and 94.4%, and 87.4 and 83.1%, respectively.
MV surgery, both minimally invasive and via sternotomy, is associated with high repair rates, excellent perioperative outcomes, and long-term survival. Data underscore the effectiveness of surgical repair in managing MR, even in the era of advancing interventional techniques.
外科二尖瓣修复术是治疗严重原发性二尖瓣反流(MR)的金标准。鉴于经皮技术的快速发展,当前的外科手术结果数据对于支持基于心脏团队的决策至关重要。
本回顾性、大容量、单中心研究分析了 1779 例原发性 MR 的早期发病率和死亡率、术后瓣膜功能以及二尖瓣(MV)修复后的长期生存率。手术于 2009 年至 2022 年进行。手术方法包括完全胸骨切开术(FS)和右侧小开胸术(微创心脏 [MIC] 手术)。
在这些手术中(平均年龄:59.9 [标准差:11.4] 岁;71.5%为男性),85.6%( = 1527)为小开胸术。849 例患者(47.7%)同时进行了其他手术,包括三尖瓣和/或房间隔缺损修复、冷冻消融和心房附件闭合。大多数患者不需要红细胞浓缩物。纵隔炎和再次开胸治疗出血的发生率分别为 0.1%和 4.3%。12 例患者(0.7%)因修复失败需要在出院前再次手术。无中重度以上 MR 的比例 > 99%。30 天死亡率为 0.2%,两组之间无显著差异( = 0.37)。中位随访时间为 48.2 个月,完整性为 95.9%。两组之间的长期生存率相似( = 0.21)。在 FS 和 MIC 组中,1、5 和 10 年生存率分别为 98.8%和 98.8%、92.9%和 94.4%以及 87.4%和 83.1%。
MV 手术,无论是微创还是经胸骨切开术,都具有较高的修复率、出色的围手术期结果和长期生存率。这些数据强调了外科修复在治疗 MR 方面的有效性,即使在介入技术不断发展的时代也是如此。