Bakir Nadia H, Bernabei Annalisa, Burns Daniel J P, Blackstone Eugene H, Houghtaling Penny L, DiPaola Linda M, Chen Jacky H K, Hage Ali, Svensson Lars G, Gillinov A Marc
Department of Thoracic and Cardiovascular Surgery, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.
Department of Thoracic and Cardiovascular Surgery, Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio; Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
J Thorac Cardiovasc Surg. 2025 Jul;170(1):177-186.e3. doi: 10.1016/j.jtcvs.2024.08.029. Epub 2024 Aug 26.
To determine the durability of mitral valve repair (MVr) with complete ring or flexible band annuloplasty in patients with atrial functional mitral regurgitation (AFMR) due to atrial fibrillation (AF) and identify risk factors associated with postoperative recurrence of mitral regurgitation.
Between January 1, 2000, and January 1, 2023, 194 adults with a history of AF underwent MVr with annuloplasty alone for moderate/severe AFMR. Exclusion criteria were prior cardiac surgery, additional repair techniques, ejection fraction <45%, ischemic heart disease, aortic valve disease, mitral annular calcification, and concomitant procedures other than surgical ablation or tricuspid repair/replacement. The durability of annuloplasty was assessed using longitudinal analysis of postoperative echocardiographic data.
Complete ring annuloplasty was performed in 126 of 194 patients (65%); partial ring (posterior band) in the other 68 (35%). Concomitantly, 124 of the 194 patients underwent tricuspid valve surgery, and 173 (89%) had a procedure for AF, including biatrial Cox-Maze III/IV lesion set in 152 (88%) and pulmonary vein isolation in 21 (12%). All patients were discharged with no/trace MR. Freedom from moderate/severe MR after repair with annuloplasty alone was 89% at 10 years, and no significant differences were noted between complete and partial ring annuloplasty (early, P = .41; late, P = .92). Forty-eight percent of patients developed AF at 3 months or longer after surgery, and the presence of postoperative AF was not associated with a greater likelihood of recurrence of MR (P = .15). Freedom from mitral reintervention was 96% at 10 years.
In appropriate patients with AFMR, the long-term durability of annuloplasty is excellent with complete ring and posterior band annuloplasty techniques.
确定因心房颤动(AF)导致心房功能性二尖瓣反流(AFMR)的患者采用完整环或柔性带瓣环成形术进行二尖瓣修复(MVr)的耐久性,并确定与二尖瓣反流术后复发相关的危险因素。
在2000年1月1日至2023年1月1日期间,194例有AF病史的成人因中度/重度AFMR单独接受了瓣环成形术的MVr。排除标准为既往心脏手术史、其他修复技术、射血分数<45%、缺血性心脏病、主动脉瓣疾病、二尖瓣环钙化以及除手术消融或三尖瓣修复/置换以外的同期手术。使用术后超声心动图数据的纵向分析评估瓣环成形术的耐久性。
194例患者中有126例(65%)进行了完整环瓣环成形术;其余68例(35%)进行了部分环(后带)瓣环成形术。同时,194例患者中有124例接受了三尖瓣手术,173例(89%)进行了AF手术,其中152例(88%)进行了双房Cox-Maze III/IV病变组手术,21例(12%)进行了肺静脉隔离术。所有患者出院时无/微量二尖瓣反流。单独采用瓣环成形术修复后10年无中度/重度二尖瓣反流的比例为89%,完整环和部分环瓣环成形术之间无显著差异(早期,P = 0.41;晚期,P = 0.92)。48%的患者在术后3个月或更长时间出现AF,术后AF的存在与二尖瓣反流复发的可能性增加无关(P = 0.15)。10年免于二尖瓣再次干预的比例为96%。
在合适的AFMR患者中,完整环和后带瓣环成形术技术的瓣环成形术长期耐久性良好。