Rigatou Anastasia, Christodoulou Konstantinos C, Zlatidou Xafnoula, Nikolakakis Ioannis
Computed Tomography and MRI Department, Sismanogleio General Hospital, Athens, GRC.
Laboratory of Anatomy, School of Medicine, Democritus University of Thrace, Alexandroupolis, GRC.
Cureus. 2024 Jan 13;16(1):e52219. doi: 10.7759/cureus.52219. eCollection 2024 Jan.
With an estimated incidence of one in 10,000 to one in 50,000 patients, Situs inversus totalis (SIT) is a rare innate anomaly, portraying a mirror image of the normal anatomy, as the cardiac position and abdominal viscera are completely inverted. Despite the fact that physicians and researchers have been dealing with the SARS-CoV-2 pandemic for three years, there is a lack of published data examining the potential effects of anatomic variations on coronavirus disease 2019 (COVID-19) infection. This study aimed to contribute to this domain by presenting a rare case of a COVID-19 infection coexisting with SIT as one of the very few cases reporting the simultaneous presence of the two pathologies. We sought to present this case of COVID-19 in a quinquagenarian female, in whom SIT was an incidental radiological finding. The reversed anatomy did not seem to affect the clinical progression of the virus. However, due to the lack of scientific evidence, the potential long-term effects, if any, of COVID-19 on SIT cannot be predicted. The recognition of the mirror pattern will offer a personalized treatment plan, reducing the risk of severe complications and management mishaps.
全内脏反位(SIT)的估计发病率为万分之一至五万分之一,是一种罕见的先天性异常,其心脏位置和腹部脏器完全反转,呈现出正常解剖结构的镜像。尽管医生和研究人员应对新冠疫情已达三年,但仍缺乏已发表的数据来研究解剖结构变异对2019冠状病毒病(COVID-19)感染的潜在影响。本研究旨在通过呈现一例罕见的COVID-19感染与SIT并存的病例,为该领域做出贡献,这是极少数同时报告这两种病症的病例之一。我们试图介绍一名五十多岁女性的COVID-19病例,其SIT是偶然的影像学发现。解剖结构反转似乎并未影响病毒的临床进展。然而,由于缺乏科学证据,无法预测COVID-19对SIT的潜在长期影响(如有)。识别镜像模式将提供个性化治疗方案,降低严重并发症和管理失误的风险。