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一名8个月大患有房室间隔缺损、右位心及内脏反位且并发严重急性营养不良的婴儿的罕见病例。

A Rare Case of Dextrocardia With Atrioventricular Septal Defect and Situs Inversus in an 8-Month-Old Infant Complicated by Severe Acute Malnutrition.

作者信息

Kassa Michael Tesfaye, Ahmed Nuru Mohamed, Shukri Mohamed Abdirahman, Abdikadir Fatumo Mohamed

机构信息

Department of Pediatrics Degehabur General Hospital Degehabur Ethiopia.

Department of Radiology Degehabur General Hospital Degehabur Ethiopia.

出版信息

Clin Case Rep. 2025 Jul 30;13(8):e70604. doi: 10.1002/ccr3.70604. eCollection 2025 Aug.

DOI:10.1002/ccr3.70604
PMID:40746775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12311224/
Abstract

The key clinical message in this case report highlights the rare coexistence of situs inversus totalis, dextrocardia, atrioventricular septal defect, and severe acute malnutrition in an Ethiopian infant. It underscores the need for heightened awareness, timely diagnosis, and integrated management strategies for such complex congenital and nutritional disorders and emphasizes the need for early surgical referral in resource-limited settings, as delayed intervention worsens outcomes.

摘要

本病例报告中的关键临床信息凸显了一名埃塞俄比亚婴儿罕见地同时存在完全性内脏反位、右位心、房室间隔缺损和严重急性营养不良的情况。它强调了对于此类复杂先天性和营养性疾病需要提高认识、及时诊断以及采取综合管理策略，并强调在资源有限的环境中早期进行手术转诊的必要性，因为延迟干预会使预后恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/2171ad9ba972/CCR3-13-e70604-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/9e6049737c73/CCR3-13-e70604-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/0638bf2ff121/CCR3-13-e70604-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/2ae49da1e0ad/CCR3-13-e70604-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/2a37e88faf4c/CCR3-13-e70604-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/2171ad9ba972/CCR3-13-e70604-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/9e6049737c73/CCR3-13-e70604-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/0638bf2ff121/CCR3-13-e70604-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/2ae49da1e0ad/CCR3-13-e70604-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/2a37e88faf4c/CCR3-13-e70604-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2435/12311224/2171ad9ba972/CCR3-13-e70604-g001.jpg

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本文引用的文献

1
A Case Report of Dextrocardia with Situs Inversus: A Rare Condition and Its Clinical Importance.右旋心伴内脏反位病例报告：一种罕见病症及其临床意义
Case Rep Med. 2024 Apr 4;2024:2435938. doi: 10.1155/2024/2435938. eCollection 2024.
2
Dextrocardia With Situs Inversus in a COVID-19 Patient.一名新冠肺炎患者出现右位心伴内脏转位
Cureus. 2024 Jan 13;16(1):e52219. doi: 10.7759/cureus.52219. eCollection 2024 Jan.
3
Situs Inversus Totalis: A Clinical Review.完全性内脏反位：临床综述
Int J Gen Med. 2022 Mar 3;15:2437-2449. doi: 10.2147/IJGM.S295444. eCollection 2022.
4
Imaging findings in a case of situs inversus totalis.全内脏转位一例的影像学表现。
BJR Case Rep. 2021 Mar 4;7(4):20200202. doi: 10.1259/bjrcr.20200202. eCollection 2021 Jul 16.
5
Assessment of Nutritional Status of Children With Congenital Heart Disease: A Comparative Study.先天性心脏病患儿营养状况评估：一项比较研究。
Front Nutr. 2021 Sep 17;8:644030. doi: 10.3389/fnut.2021.644030. eCollection 2021.
6
Structural Heart Issues in Dextrocardia: Situs Type Matters.右位心的结构性心脏问题：心位类型很重要。
Ochsner J. 2021 Spring;21(1):111-114. doi: 10.31486/toj.19.0119.
7
Acute Malnutrition in Children: Pathophysiology, Clinical Effects and Treatment.儿童急性营养不良：病理生理学、临床影响和治疗。
Nutrients. 2020 Aug 12;12(8):2413. doi: 10.3390/nu12082413.
8
Severely malnourished children with a low weight-for-height have a higher mortality than those with a low mid-upper-arm-circumference: I. Empirical data demonstrates Simpson's paradox.严重营养不良且身高体重比低的儿童比中上臂围低的儿童死亡率更高：I. 经验数据证明辛普森悖论。
Nutr J. 2018 Sep 15;17(1):79. doi: 10.1186/s12937-018-0384-4.
9
Atrioventricular septal defects.房室间隔缺损
Ann Card Anaesth. 2018 Jan-Mar;21(1):1-3. doi: 10.4103/aca.ACA_219_17.
10
Atrioventricular septal defect: From embryonic development to long-term follow-up.房室间隔缺损：从胚胎发育到长期随访
Int J Cardiol. 2016 Jan 1;202:784-95. doi: 10.1016/j.ijcard.2015.09.081. Epub 2015 Sep 26.