Department of General Medicine, Saga University Hospital, Saga, Japan.
Graduate School of Public Health, Shizuoka Graduate University of Public Health, Shizuoka, Japan.
Clin Interv Aging. 2024 Feb 7;19:175-188. doi: 10.2147/CIA.S441235. eCollection 2024.
We conducted a pilot study in an acute care hospital and developed the Saga Fall Risk Model 2 (SFRM2), a fall prediction model comprising eight items: Bedriddenness rank, age, sex, emergency admission, admission to the neurosurgery department, history of falls, independence of eating, and use of hypnotics. The external validation results from the two hospitals showed that the area under the curve (AUC) of SFRM2 may be lower in other facilities. This study aimed to validate the accuracy of SFRM2 using data from eight hospitals, including chronic care hospitals, and adjust the coefficients to improve the accuracy of SFRM2 and validate it.
This study included all patients aged ≥20 years admitted to eight hospitals, including chronic care, acute care, and tertiary hospitals, from April 1, 2018, to March 31, 2021. In-hospital falls were used as the outcome, and the AUC and shrinkage coefficient of SFRM2 were calculated. Additionally, SFRM2.1, which was modified from the coefficients of SFRM2 using logistic regression with the eight items comprising SFRM2, was developed using two-thirds of the data randomly selected from the entire population, and its accuracy was validated using the remaining one-third portion of the data.
Of the 124,521 inpatients analyzed, 2,986 (2.4%) experienced falls during hospitalization. The median age of all inpatients was 71 years, and 53.2% were men. The AUC of SFRM2 was 0.687 (95% confidence interval [CI]:0.678-0.697), and the shrinkage coefficient was 0.996. SFRM2.1 was created using 81,790 patients, and its accuracy was validated using the remaining 42,731 patients. The AUC of SFRM2.1 was 0.745 (95% CI: 0.731-0.758).
SFRM2 showed good accuracy in predicting falls even on validating in diverse populations with significantly different backgrounds. Furthermore, the accuracy can be improved by adjusting the coefficients while keeping the model's parameters fixed.
我们在一家急症医院进行了一项试点研究,并开发了 Saga 跌倒风险模型 2(SFRM2),这是一个包含 8 个项目的跌倒预测模型:卧床等级、年龄、性别、急诊入院、神经外科入院、跌倒史、进食独立性和使用催眠剂。来自两家医院的外部验证结果表明,SFRM2 的曲线下面积(AUC)在其他设施中可能较低。本研究旨在使用来自包括慢性病医院在内的 8 家医院的数据验证 SFRM2 的准确性,并调整系数以提高 SFRM2 的准确性并对其进行验证。
本研究纳入了 2018 年 4 月 1 日至 2021 年 3 月 31 日期间,8 家医院(包括慢性病、急症和三级医院)所有≥20 岁的住院患者。以院内跌倒为结局,计算 SFRM2 的 AUC 和收缩系数。此外,使用包含 SFRM2 的 8 个项目的逻辑回归对 SFRM2 的系数进行修正,得到 SFRM2.1,并使用从整个人群中随机抽取的三分之二的数据进行开发,然后使用剩余的三分之一数据对其准确性进行验证。
在分析的 124521 名住院患者中,2986 名(2.4%)在住院期间发生跌倒。所有住院患者的中位年龄为 71 岁,53.2%为男性。SFRM2 的 AUC 为 0.687(95%置信区间[CI]:0.678-0.697),收缩系数为 0.996。使用 81790 名患者创建了 SFRM2.1,并使用剩余的 42731 名患者对其准确性进行验证。SFRM2.1 的 AUC 为 0.745(95% CI:0.731-0.758)。
即使在验证具有显著不同背景的不同人群时,SFRM2 也显示出良好的跌倒预测准确性。此外,通过固定模型参数调整系数可以提高准确性。