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Role of Extracellular Vesicles in Immunity and Host Defense.细胞外囊泡在免疫和宿主防御中的作用。
Immunol Invest. 2024 Jan;53(1):10-25. doi: 10.1080/08820139.2024.2312896. Epub 2024 Feb 13.
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Antigen Presentation by Extracellular Vesicles from Professional Antigen-Presenting Cells.专业抗原提呈细胞来源的细胞外囊泡的抗原呈递。
Annu Rev Immunol. 2018 Apr 26;36:435-459. doi: 10.1146/annurev-immunol-041015-055700. Epub 2018 Jan 31.
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Extracellular Vesicles and Immunity: At the Crossroads of Cell Communication.细胞外囊泡与免疫：细胞通讯的十字路口
Int J Mol Sci. 2024 Jan 18;25(2):1205. doi: 10.3390/ijms25021205.
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Gift bags from the sentinel cells of the immune system: The diverse role of dendritic cell-derived extracellular vesicles.免疫细胞的“礼物袋”：树突状细胞衍生的细胞外囊泡的多种作用。
J Leukoc Biol. 2022 Apr;111(4):903-920. doi: 10.1002/JLB.3RU1220-801R. Epub 2021 Oct 26.
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Extracellular vesicles in allograft rejection and tolerance.同种异体移植排斥与耐受中的细胞外囊泡。
Cell Immunol. 2020 Mar;349:104063. doi: 10.1016/j.cellimm.2020.104063. Epub 2020 Feb 8.
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Extracellular vesicles derived from antigen-presenting cells pulsed with foot and mouth virus vaccine-antigens act as carriers of viral proteins and stimulate B cell response.抗原呈递细胞来源的细胞外囊泡负载口蹄疫疫苗抗原可作为病毒蛋白的载体，并刺激 B 细胞应答。
Front Immunol. 2024 Aug 8;15:1440667. doi: 10.3389/fimmu.2024.1440667. eCollection 2024.
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Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo.来源于沙门氏菌感染细胞的抗原包被的宿主细胞外囊泡在体内刺激病原体特异性 Th1 型反应。
PLoS Pathog. 2021 May 6;17(5):e1009465. doi: 10.1371/journal.ppat.1009465. eCollection 2021 May.
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Outer membrane vesicles engineered to express membrane-bound antigen program dendritic cells for cross-presentation to CD8 T cells.经工程改造表达膜结合抗原的外膜囊泡可对树突状细胞进行交叉呈递，以激活 CD8 T 细胞。
Acta Biomater. 2019 Jun;91:248-257. doi: 10.1016/j.actbio.2019.04.033. Epub 2019 Apr 17.
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Extracellular vesicles- crucial players in human pregnancy.细胞外囊泡——人类妊娠中的关键角色。
Placenta. 2023 Sep 7;140:30-38. doi: 10.1016/j.placenta.2023.07.006. Epub 2023 Jul 26.
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Communication is key: extracellular vesicles as mediators of infection and defence during host-microbe interactions in animals and plants.沟通是关键：细胞外囊泡作为动物和植物中宿主-微生物相互作用过程中感染和防御的介质。
FEMS Microbiol Rev. 2022 Jan 18;46(1). doi: 10.1093/femsre/fuab044.
引用本文的文献
1
Isolation of bacterial extracellular vesicles from raw samples using a portable microstructured electrochemical device.使用便携式微结构电化学装置从原始样品中分离细菌细胞外囊泡。
Drug Deliv Transl Res. 2025 Aug 26. doi: 10.1007/s13346-025-01954-1.
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Immune activation and regulation mediated by immune cell-derived EVs (iEVs).由免疫细胞衍生的细胞外囊泡（iEVs）介导的免疫激活和调节。
Essays Biochem. 2025 May 20. doi: 10.1042/EBC20253005.
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Congenital Zika Syndrome: Insights from Integrated Proteomic and Metabolomic Analysis.先天性寨卡综合征：蛋白质组学与代谢组学综合分析的见解
Biomolecules. 2024 Dec 30;15(1):32. doi: 10.3390/biom15010032.
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Exosomes and Macrophages: Bidirectional Mutual Regulation in the Treatment of Diabetic Complications.外泌体与巨噬细胞：糖尿病并发症治疗中的双向相互调节
Cell Mol Bioeng. 2024 Aug 31;17(4):243-261. doi: 10.1007/s12195-024-00816-z. eCollection 2024 Aug.
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Clodronate Reduces ATP-Containing Microvesicle Releasing Induced by Nociceptive Stimuli in Human Keratinocytes.氯膦酸盐减少伤害性刺激诱导的人角质形成细胞释放含 ATP 的微囊泡。
Int J Mol Sci. 2024 Aug 2;25(15):8435. doi: 10.3390/ijms25158435.
本文引用的文献
1
The role and mechanisms of gram-negative bacterial outer membrane vesicles in inflammatory diseases.革兰氏阴性菌外膜囊泡在炎症性疾病中的作用及其机制。
Front Immunol. 2023 Jun 16;14:1157813. doi: 10.3389/fimmu.2023.1157813. eCollection 2023.
2
Engineered bacterial outer membrane vesicles encapsulating oncolytic adenoviruses enhance the efficacy of cancer virotherapy by augmenting tumor cell autophagy.工程化细菌外膜囊泡包裹溶瘤腺病毒通过增强肿瘤细胞自噬增强癌症病毒疗法的疗效。
Nat Commun. 2023 May 22;14(1):2933. doi: 10.1038/s41467-023-38679-z.
3
Infection-induced extracellular vesicles evoke neuronal transcriptional and epigenetic changes.感染诱导的细胞外囊泡引起神经元的转录和表观遗传变化。
Sci Rep. 2023 Apr 27;13(1):6913. doi: 10.1038/s41598-023-34074-2.
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Outer membrane vesicles: A bacterial-derived vaccination system.外膜囊泡：一种源自细菌的疫苗接种系统。
Front Microbiol. 2022 Dec 21;13:1029146. doi: 10.3389/fmicb.2022.1029146. eCollection 2022.
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Bacterial outer membrane vesicles as a candidate tumor vaccine platform.细菌外膜囊泡作为候选肿瘤疫苗平台。
Front Immunol. 2022 Sep 9;13:987419. doi: 10.3389/fimmu.2022.987419. eCollection 2022.
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Outer membrane vesicles of trigger NLRP3 inflammasome and induce neuroinflammation, tau phosphorylation, and memory dysfunction in mice.外膜囊泡触发 NLRP3 炎性体，导致小鼠神经炎症、tau 磷酸化和记忆功能障碍。
Front Cell Infect Microbiol. 2022 Aug 9;12:925435. doi: 10.3389/fcimb.2022.925435. eCollection 2022.
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The roles of extracellular vesicles in the immune system.细胞外囊泡在免疫系统中的作用。
Nat Rev Immunol. 2023 Apr;23(4):236-250. doi: 10.1038/s41577-022-00763-8. Epub 2022 Aug 4.
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The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis.肠道微生物组通过 cGAS-STING-IFN-I 轴诱导全身性抗病毒免疫。
Immunity. 2022 May 10;55(5):847-861.e10. doi: 10.1016/j.immuni.2022.04.006.
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Recent Progress Towards a Gonococcal Vaccine.淋球菌疫苗的最新研究进展
Front Cell Infect Microbiol. 2022 Apr 11;12:881392. doi: 10.3389/fcimb.2022.881392. eCollection 2022.
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Outer membrane vesicles produced by pathogenic strains of block autophagic flux and exacerbate inflammasome activation.致病性菌株产生的外膜囊泡会阻断自噬流，并加剧炎症小体的激活。
Autophagy. 2022 Dec;18(12):2913-2925. doi: 10.1080/15548627.2022.2054040. Epub 2022 Apr 7.
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