From the Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
Clin Nucl Med. 2024 Apr 1;49(4):371-372. doi: 10.1097/RLU.0000000000005072. Epub 2024 Feb 1.
Coexistence of Langerhans cell histiocytosis and ganglioneuroblastoma is rare and seldom reported in the literature. A 3-year-old girl with Langerhans cell histiocytosis underwent 18 F-FDG PET/CT imaging for staging, which demonstrated significant 18 F-FDG accumulation in the mandibles. Unexpectedly, a mild hypermetabolic soft mass was detected in the upper retroperitoneum. Results of surgical pathology of the abdominal mass were consistent with ganglioneuroblastoma.
朗格汉斯细胞组织细胞增生症与神经母细胞瘤共存非常罕见,文献中鲜有报道。一位 3 岁的朗格汉斯细胞组织细胞增生症女孩为了分期接受了 18 F-FDG PET/CT 成像,结果显示下颌骨有明显的 18 F-FDG 摄取。出乎意料的是,在上腹部后腹膜区发现一个轻度高代谢的软组织肿块。腹部肿块的手术病理结果与神经母细胞瘤一致。