Zhang Limin, You Jianing, Huang Yiqing, Jing Ruiqi, He Yifei, Wen Yujie, Zheng Lulu, Zhao Yong
College of Basic Medical, Shanxi University of Chinese Medicine, Taiyuan, Shanxi, China.
The Faculty of Applied Science and Engineering, University of Toronto, Toronto, Ontario, Canada.
Comb Chem High Throughput Screen. 2025;28(4):664-674. doi: 10.2174/0113862073293191240212091028.
Dysmenorrhea is one of the most common ailments affecting young and middle-aged women, significantly impacting their quality of life. Traditional Chinese Medicine (TCM) offers unique advantages in treating dysmenorrhea. However, an accurate diagnosis is essential to ensure correct treatment. This research integrates the age-old wisdom of TCM with modern Machine Learning (ML) techniques to enhance the precision and efficiency of dysmenorrhea syndrome differentiation, a pivotal process in TCM diagnostics and treatment planning.
A total of 853 effective cases of dysmenorrhea were retrieved from the CNKI database, including patients' syndrome types, symptoms, and features, to establish the TCM information database of dysmenorrhea. Subsequently, 42 critical features were isolated from a potential set of 86 using a selection procedure augmented by Python's Scikit-Learn Library. Various machine learning models were employed, including Logistic Regression, Random Forest Classifier, Support Vector Machine (SVM), K-Nearest Neighbors (KNN), and Artificial Neural Networks (ANN), each chosen for their potential to unearth complex patterns within the data.
Based on accuracy, precision, recall, and F1-score metrics, SVM emerged as the most effective model, showcasing an impressive precision of 98.29% and an accuracy of 98.24%. This model's analytical prowess not only highlighted the critical features pivotal to the syndrome differentiation process but also stands to significantly aid clinicians in formulating personalized treatment strategies by pinpointing nuanced symptoms with high precision.
The study paves the way for a synergistic approach in TCM diagnostics, merging ancient wisdom with computational acuity, potentially innovating the diagnosis and treatment mode of TCM. Despite the promising outcomes, further research is needed to validate these models in real-world settings and extend this approach to other diseases addressed by TCM.
痛经是影响中青年女性的最常见疾病之一,严重影响她们的生活质量。中医在治疗痛经方面具有独特优势。然而,准确的诊断对于确保正确治疗至关重要。本研究将中医的古老智慧与现代机器学习(ML)技术相结合,以提高痛经辨证的准确性和效率,痛经辨证是中医诊断和治疗规划中的关键过程。
从中国知网数据库中检索出853例痛经有效病例,包括患者的证型、症状和特征,建立痛经中医信息数据库。随后,使用Python的Scikit-Learn库增强的选择程序,从86个潜在特征中分离出42个关键特征。采用了多种机器学习模型,包括逻辑回归、随机森林分类器、支持向量机(SVM)、K近邻(KNN)和人工神经网络(ANN),每个模型都因其挖掘数据中复杂模式的潜力而被选用。
基于准确率、精确率、召回率和F1分数指标,SVM成为最有效的模型,展现出令人印象深刻的98.29%的精确率和98.24%的准确率。该模型的分析能力不仅突出了辨证过程中的关键特征,还通过高精度地找出细微症状,极大地有助于临床医生制定个性化治疗策略。
该研究为中医诊断中的协同方法铺平了道路,将古老智慧与计算敏锐性相结合,有可能创新中医诊断和治疗模式。尽管取得了令人鼓舞的成果,但仍需要进一步研究在实际环境中验证这些模型,并将这种方法扩展到中医治疗的其他疾病。