Maiya G Arun, Jadhav Radhika Aditya, Yadav K Hrishikesh, Hande H Manjunatha, Hebbar Harishchandra, Mohan Karthik
Department of Physiotherapy, Centre for Diabetic Foot Care and Research, Manipal College of Health Professions, Manipal Academy of Higher Education, Karnataka, Manipal, 576 104, India.
Centre for Healthcare Entrepreneurship, Indian Institute of Technology, Hyderabad, India.
Curr Diabetes Rev. 2025;21(3):1-6. doi: 10.2174/0115733998244000231106040749.
Photobiomodulation (PBM) or Low-level laser is used to treat diabetic foot complications. The existing method of laser application to the foot did not cover the foot's entire area to improve the foot's microcirculation. Therefore, we have developed a cost-effective Special LASER Shoe device, focusing exclusively on the entire foot region to manage neuropathic pain and other symptoms in individuals with type 2 diabetes mellitus.
The main objective of the present study was to evaluate the effect of this newly developed special laser shoe PBM on neuropathic pain and plantar pressure profile in individuals with type 2 diabetes mellitus with neuropathy.
We included 60 participants with diabetic peripheral neuropathy of both genders and age more than 20 years. Participants were treated with PBM by a specially designed novel Laser Shoe. Outcomes were clinical variables like Vibration Perception Threshold (VPT), Visual Analogue Scale (VAS), Michigan neuropathy screening instrument A&B, Ankle-Brachial Index (ABI), and Static dynamic gait parameters.
Participants were with an average age of 62, and the average duration of diabetes was 11 years. Analysis showed a significant difference in VPT, VAS, Michigan neuropathic screening inventory, and ankle-brachial index (P < 0.05).
We conclude that Novel laser shoe photobiomodulation using 'Laser Shoe' effectively reduces peripheral neuropathic pain. It is also effective in reducing average and maximum plantar pressure. Reduction in neuropathic pain and improvement in plantar pressure distribution can reduce further complications.
光生物调节（PBM）或低强度激光用于治疗糖尿病足并发症。现有的将激光应用于足部的方法并未覆盖足部的整个区域，以改善足部的微循环。因此，我们开发了一种经济高效的特殊激光鞋装置，专门针对整个足部区域，以管理2型糖尿病患者的神经性疼痛和其他症状。
本研究的主要目的是评估这种新开发的特殊激光鞋PBM对2型糖尿病伴神经病变患者的神经性疼痛和足底压力分布的影响。
我们纳入了60名年龄超过20岁的患有糖尿病周围神经病变的男女参与者。参与者使用专门设计的新型激光鞋进行PBM治疗。结果包括临床变量，如振动感觉阈值（VPT）、视觉模拟评分（VAS）、密歇根神经病变筛查仪器A和B、踝肱指数（ABI）以及静态和动态步态参数。
参与者的平均年龄为62岁，平均糖尿病病程为11年。分析显示，VPT、VAS、密歇根神经病变筛查量表和踝肱指数存在显著差异（P<0.05）。
我们得出结论，使用“激光鞋”进行新型激光鞋光生物调节可有效减轻周围神经性疼痛。它还能有效降低平均和最大足底压力。神经性疼痛的减轻和足底压力分布的改善可以减少进一步的并发症。
