Department of Medicine, Diakonhjemmet Hospital, Oslo, Norway.
Department of Rehabilitation Science and Health Technology, Oslo Metropolitan University (OsloMet), Oslo, Norway.
Aging Clin Exp Res. 2024 Feb 14;36(1):41. doi: 10.1007/s40520-024-02699-6.
Delirium is common in geriatric inpatients and associated with poor outcomes. Hospitalization is associated with low levels of physical activity. Motor symptoms are common in delirium, but how delirium affects physical activity remains unknown.
To investigate differences in physical activity between geriatric inpatients with and without delirium.
We included acutely admitted patients ≥ 75 years in a prospective observational study at a medical geriatric ward at a Norwegian University Hospital. Delirium was diagnosed according to the DSM-5 criteria. Physical activity was measured by an accelerometer-based device worn on the right thigh. The main outcome was time in upright position (upright time) per 24 h (00.00 to 23.59) on the first day of hospitalization with verified delirium status. Group differences were analysed using t test.
We included 237 patients, mean age 86.1 years (Standard Deviation (SD) 5.1), and 73 patients (30.8%) had delirium. Mean upright time day 1 for the entire group was 92.2 min (SD 84.3), with 50.9 min (SD 50.7) in the delirium group and 110.6 min (SD 89.7) in the no-delirium group, mean difference 59.7 minutes, 95% Confidence Interval 41.6 to 77.8, p value < 0.001.
Low levels of physical activity in patients with delirium raise the question if immobilization may contribute to poor outcomes in delirium. Future studies should investigate if mobilization interventions could improve outcomes of delirium.
In this sample of geriatric inpatients, the group with delirium had lower levels of physical activity than the group without delirium.
谵妄在老年住院患者中很常见，与不良结局相关。住院与低水平的身体活动有关。运动症状在谵妄中很常见，但谵妄如何影响身体活动尚不清楚。
调查患有和不患有谵妄的老年住院患者之间身体活动的差异。
我们纳入了一家挪威大学医院内科老年病房中急性入院的年龄≥75 岁的患者。根据 DSM-5 标准诊断谵妄。使用佩戴在右大腿上的基于加速度计的设备测量身体活动。主要结局是在第一天住院时佩戴设备的情况下，谵妄状态得到验证的患者在 24 小时内处于直立位置（直立时间）的时间（00.00 至 23.59）。使用 t 检验分析组间差异。
我们纳入了 237 名患者，平均年龄 86.1 岁（标准差（SD）5.1），73 名患者（30.8%）患有谵妄。整个组在第一天的平均直立时间为 92.2 分钟（SD 84.3），谵妄组为 50.9 分钟（SD 50.7），无谵妄组为 110.6 分钟（SD 89.7），平均差异为 59.7 分钟，95%置信区间为 41.6 至 77.8，p 值<0.001。
患有谵妄的患者身体活动水平较低，这引发了一个问题，即是否固定不动可能会导致谵妄的不良结局。未来的研究应调查是否可以通过动员干预来改善谵妄的结局。
在本老年住院患者样本中，患有谵妄的组的身体活动水平低于无谵妄的组。
