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[志愿者吸入暴露模型中邻苯二甲酸盐蓄积与消除的动力学研究]

[Kinetic study of phthalate accumulation and elimination in a model of inhalational exposure in volunteers].

作者信息

Kodeikh N

出版信息

Probl Khig. 1985;10:81-7.

PMID:3835570
Abstract

Studies were performed on volunteers exposed to 0.5 and 2 mg/m3 diethylhexyl phthalate for a period of 5 days. The accumulation of diethylhexyl phthalate in blood and its elimination with urine was traced. Accumulation of phthalates in the organism was established even in lower MAC concentration of 0.5 mg/m3, which puts the problem of reevaluation of this norm (1 mg/m3).

摘要

对暴露于0.5和2毫克/立方米邻苯二甲酸二乙酯5天的志愿者进行了研究。追踪了邻苯二甲酸二乙酯在血液中的积累及其随尿液的排出情况。即使在较低的职业接触限值浓度0.5毫克/立方米下,也确定了邻苯二甲酸盐在生物体中的积累,这就提出了重新评估该标准(1毫克/立方米)的问题。

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