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[采用免疫酶法(ELISA)检测肺结核患者血清中结核菌素纯蛋白衍生物IgG抗体的研究]

[Study of IgG antibodies to PPD with an immunoenzyme method (ELISA) in the serum of patients with pulmonary tuberculosis].

作者信息

Fantoni M, Altieri A, Nervo P

出版信息

Quad Sclavo Diagn. 1985 Sep;21(3):349-53.

PMID:3835574
Abstract

ELISA has been used for the detection of IgG antibodies against PPD in 48 patients with pulmonary tuberculosis, in 10 individuals with previously treated tuberculosis and clinically recovered, in 22 PPD skin-test positive healthy volunteers and in 48 blood donors with unknown PPD skin-test. Positivity was obtained in 29 patients (83%) with active tuberculosis, in one patient (10%) with clinical recovery, in none of the healthy controls. This technique may have a potential diagnostic relevance in evaluating patients with suspected pulmonary tuberculosis.

摘要

酶联免疫吸附测定(ELISA)已用于检测48例肺结核患者、10例曾接受过治疗且临床已康复的肺结核患者、22例结核菌素纯蛋白衍生物(PPD)皮肤试验阳性的健康志愿者以及48例PPD皮肤试验情况不明的献血者体内抗PPD的IgG抗体。29例(83%)活动性肺结核患者检测结果呈阳性,1例(10%)临床康复患者检测结果呈阳性,健康对照者检测结果均为阴性。该技术在评估疑似肺结核患者时可能具有潜在的诊断意义。

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