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酒渣鼻患者的护肤习惯及可能的酒渣鼻诱发因素调查:一项前瞻性病例对照研究。

Investigation of skincare habits and possible rosacea triggers of patients with rosacea: A prospective case-control study.

作者信息

Guder Husna, Guder Semih

机构信息

Department of Dermatology, Maltepe University Faculty of Medicine, Istanbul, Turkiye.

Department of Dermatology, Bezmialem Vakif University Faculty of Medicine, Istanbul, Turkiye.

出版信息

North Clin Istanb. 2024 Jan 31;11(1):27-37. doi: 10.14744/nci.2023.33410. eCollection 2024.

DOI:10.14744/nci.2023.33410
PMID:38357320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10861432/
Abstract

OBJECTIVE

Skincare is a part of rosacea treatment; patients benefit from complementary dermo-cosmetic care as well as medical treatments. Some skincare habits are known to trigger and exacerbate rosacea, but there are very few epidemiological studies on this matter.

METHODS

A total of 200 people, including 100 patients with rosacea and 100 controls, were included in the study. We questioned the methods used by the participants in daily facial cleansing. Sun and heat exposure, makeup habits, the history of the use of topical steroids, and outdoor working status were noted. A dermoscopic examination, a non-invasive and valuable method to evaluate the presence and severity of Demodex, was performed.

RESULTS

We evaluated 30% of our rosacea patients as erythematotelangiectatic rosacea, 13% as papulopustular rosacea, and 57% of our patients had mixed type, which could not be distinguished from one of these subtypes. In the case group, the proportion of people who used daily facial cleansers and daily soaps was lower than in the control group, while the proportion of those who cleaned their face with only water and those who used facial cleansers less frequently was higher (p<0.001). In the case group, while the rate of daily make-up and use of make-up products was lower (p=0.001, p<0.001, respectively), the rate of not wearing make-up was higher (p=0.001). The history of hot bath use was higher in the case group than in the control group (p=0.011). We found a significant relationship between the severity of plaque and dry appearance and the increase in Demodex density (p=0.007, p<0.001, respectively).

CONCLUSION

We recommend that patients with rosacea clean their faces daily with soap or facial cleansers and not take a bath with very hot water. Patients should be evaluated for increased Demodex mites, especially if skin dryness is accompanied.

摘要

目的

皮肤护理是酒渣鼻治疗的一部分;患者可从辅助性皮肤美容护理以及医学治疗中获益。已知一些皮肤护理习惯会引发并加重酒渣鼻,但关于此事的流行病学研究非常少。

方法

共有200人纳入本研究,其中包括100名酒渣鼻患者和100名对照者。我们询问了参与者日常面部清洁所使用的方法。记录了日晒和受热情况、化妆习惯、外用类固醇使用史以及户外工作状态。进行了皮肤镜检查,这是一种评估蠕形螨存在情况及严重程度的非侵入性且有价值的方法。

结果

我们将30%的酒渣鼻患者评估为红斑毛细血管扩张型酒渣鼻,13%为丘疹脓疱型酒渣鼻,57%的患者为混合型,无法从这些亚型中区分出来。在病例组中,每日使用面部清洁剂和日常肥皂的人群比例低于对照组,而仅用水洗脸以及较少使用面部清洁剂的人群比例更高(p<0.001)。在病例组中,每日化妆和使用化妆品的比例较低(分别为p=0.001,p<0.001),而不化妆的比例较高(p=0.001)。病例组使用热水浴的历史高于对照组(p=0.011)。我们发现斑块严重程度和皮肤干燥外观与蠕形螨密度增加之间存在显著关联(分别为p=0.007,p<0.001)。

结论

我们建议酒渣鼻患者每日用肥皂或面部清洁剂洗脸,不要用非常热的水洗澡。应评估患者蠕形螨是否增多,尤其是伴有皮肤干燥的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6e2/10861432/6026b2d80e0e/NCI-11-027-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6e2/10861432/6026b2d80e0e/NCI-11-027-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6e2/10861432/6026b2d80e0e/NCI-11-027-g001.jpg

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本文引用的文献

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J Cosmet Dermatol. 2023 Mar;22(3):949-957. doi: 10.1111/jocd.15470. Epub 2022 Nov 27.
2
Health Related Quality of Life of Rosacea Patients in China Assessed by Dermatology Life Quality Index and Willingness to Pay.通过皮肤病生活质量指数和支付意愿评估中国酒渣鼻患者的健康相关生活质量
Patient Prefer Adherence. 2022 Mar 6;16:659-670. doi: 10.2147/PPA.S345258. eCollection 2022.
3
Rosacea, an infectious disease: why rosacea with papulopustules should be considered a demodicosis. A narrative review.
酒渣鼻,一种传染病:为什么有丘疹脓疱的酒渣鼻应被视为蠕形螨病。一篇叙述性综述。
J Eur Acad Dermatol Venereol. 2022 Jul;36(7):987-1002. doi: 10.1111/jdv.18049. Epub 2022 Mar 31.
4
Characterization of rosacea patients in Tohoku area of Japan: Retrospective study of 340 rosacea cases.日本东北地区酒渣鼻患者的特征:340例酒渣鼻病例的回顾性研究。
J Dermatol. 2022 May;49(5):519-524. doi: 10.1111/1346-8138.16317. Epub 2022 Feb 17.
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Evaluation of demodicosis, nailfold capillaroscopy, and oxidative stress in rosacea: a case-control study.酒渣鼻患者蠕形螨病、甲襞毛细血管镜检查及氧化应激的评估:一项病例对照研究。
Postepy Dermatol Alergol. 2021 Aug;38(4):590-596. doi: 10.5114/ada.2021.108917. Epub 2021 Sep 17.
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The relationship between rosacea and smoking: A systematic review and meta-analysis.酒渣鼻与吸烟的关系:一项系统评价和荟萃分析。
Australas J Dermatol. 2021 Nov;62(4):e600-e602. doi: 10.1111/ajd.13711. Epub 2021 Sep 7.
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Massive Demodicosis of the Eyes in a Patient with Sjögren Syndrome: A Case Report.干燥综合征患者眼部重度蠕形螨病:一例报告
Acta Parasitol. 2021 Jun;66(2):677-681. doi: 10.1007/s11686-020-00297-w. Epub 2020 Oct 31.
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Dermatol Ther (Heidelb). 2020 Dec;10(6):1229-1253. doi: 10.1007/s13555-020-00458-9. Epub 2020 Oct 23.
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