Wada-Irimada Moyuka, Yamamoto Haruka, Terui Hitoshi, Omori-Shimada Ryoko, Yamazaki Emi, Kikuchi Katsuko, Aiba Setsuya, Yamasaki Kenshi
Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
J Dermatol. 2022 May;49(5):519-524. doi: 10.1111/1346-8138.16317. Epub 2022 Feb 17.
Rosacea is a chronic inflammatory skin disease with facial redness and acne-like papules and pustules. The characteristics and background of rosacea patients in Japan have not been well documented. In this study, we retrospectively collected the medical information of rosacea patients, and investigated the background, complications, exacerbating factors, and status of allergy. Between January 2010 and December 2020, 431 cases were diagnosed as rosacea or rosacea-like dermatitis. We selected 340 patients, in which we could confirm telangiectasia on facial skin. Females and males numbered 266 and 74, respectively. The average age of the first visit was 51.5 years, and the youngest and oldest were 11 and 88 years old. Among 340 cases, 323 had erythematotelangiectatic rosacea, 97 papulopustular rosacea, 20 phymatous rosacea presenting as rhinophyma, and four had symptoms of ocular rosacea. The most common complication was hay fever (93 individuals, 27.4%), and 66 (19.4%) had a medical history of contact dermatitis. Temperature differences (141 individuals, 41.5%) were the most common exacerbating factor followed by sunlight exposure (60 individuals, 17.6%). Seventy-eight individuals received allergen-specific immunoglobulin (Ig)E tests, and IgE for cedar was the most frequently observed (46 individuals, 59.0%). High frequencies of IgE for Dermatophagoides pteronyssinus or D. farinae (33 individuals, 42.3%) and house dust I (31 individuals, 39.7%) suggested that environmental conditions at home would affect rosacea symptoms. Since the facial skin is exposed to environmental stimuli every moment, this retrospective observation suggested the importance of the daily lifestyle guidance as well as medical treatments.
酒渣鼻是一种慢性炎症性皮肤病，表现为面部发红以及痤疮样丘疹和脓疱。日本酒渣鼻患者的特征和背景尚未得到充分记录。在本研究中，我们回顾性收集了酒渣鼻患者的医疗信息，并调查了其背景、并发症、加重因素和过敏状况。在2010年1月至2020年12月期间，431例被诊断为酒渣鼻或酒渣鼻样皮炎。我们选择了340例患者，其中面部皮肤有毛细血管扩张可得到确认。女性和男性分别为266例和74例。首次就诊的平均年龄为51.5岁，最年轻和最年长的分别为11岁和88岁。在340例病例中，323例为红斑毛细血管扩张型酒渣鼻，97例为丘疹脓疱型酒渣鼻，20例为鼻赘型酒渣鼻表现为鼻赘，4例有眼部酒渣鼻症状。最常见的并发症是花粉症（93例，27.4%），66例（19.4%）有接触性皮炎病史。温度差异（141例，41.5%）是最常见的加重因素，其次是阳光照射（60例，17.6%）。78例患者接受了变应原特异性免疫球蛋白（Ig）E检测，其中雪松IgE的检测频率最高（46例，59.0%）。粉尘螨或屋尘螨IgE（33例，42.3%）和屋尘I IgE（31例，39.7%）的高检测频率表明家庭环境状况会影响酒渣鼻症状。由于面部皮肤时刻暴露于环境刺激之下，这项回顾性观察提示了日常生活方式指导以及医学治疗的重要性。
