van Ooijen I M, Annink K V, Benders M J N L, Dudink J, Alderliesten T, Groenendaal F, Tataranno M L, Lequin M H, Hoogduin J M, Visser F, Raaijmakers A J E, Klomp D W J, Wiegers E C, Wijnen J P, van der Aa N E
Department of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the Netherlands.
Centre for Image Sciences, High Field MR Research, University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands.
Neuroimage Rep. 2023 Jun;3(2):100175. doi: 10.1016/j.ynirp.2023.100175.
Brain MRI in infants at ultra-high-field scanners might improve diagnostic quality, but safety should be evaluated first. In our previous study, we reported simulated specific absorption rates and acoustic noise data at 7 Tesla.
In this study, we included twenty infants between term-equivalent age and three months of age. The infants were scanned on a 7 Tesla MRI directly after their clinically indicated 3 Tesla brain MRI scan. Vital parameters, temperature, and comfort were monitored throughout the process. Brain temperature was estimated during the MRI scans using proton MR spectroscopy.
We found no significant differences in vital parameters, temperature, and comfort during and after 7 Tesla MRI scans, compared to 3 Tesla MRI scans.
These data confirm our hypothesis that scanning infants at 7 Tesla MRI appears to be safe and we identified no additional risks from scanning at 3 Tesla MRI.
在超高场扫描仪上对婴儿进行脑部磁共振成像(MRI)可能会提高诊断质量,但应首先评估安全性。在我们之前的研究中,我们报告了7特斯拉时的模拟比吸收率和声噪数据。
在本研究中,我们纳入了20名足月等效年龄至3个月大的婴儿。这些婴儿在临床指示进行3特斯拉脑部MRI扫描后,直接在7特斯拉MRI上进行扫描。在整个过程中监测生命体征参数、体温和舒适度。在MRI扫描期间使用质子磁共振波谱估计脑温。
与3特斯拉MRI扫描相比,我们发现在7特斯拉MRI扫描期间及之后,生命体征参数、体温和舒适度没有显著差异。
这些数据证实了我们的假设,即在7特斯拉MRI上扫描婴儿似乎是安全的,并且我们未发现3特斯拉MRI扫描存在额外风险。