Division of Neonatology, Department of Pediatrics, Erasmus Medical Centre-Sophia, Dr. Molewaterplein, 60 3015 GJ, Rotterdam, The Netherlands.
Pediatr Radiol. 2012 Oct;42(10):1205-11. doi: 10.1007/s00247-012-2426-y. Epub 2012 Aug 9.
Cerebral MRI performed on preterm infants at term-equivalent 30 weeks' gestational age (GA) is increasingly performed as part of standard clinical care.
We evaluated safety of these early MRI procedures.
We retrospectively collected data on patient safety of preterm infants who underwent early MRI scans. Data were collected at fixed times before and after the MRI scan. MRI procedures were carried out according to a comprehensive guideline.
A total of 52 infants underwent an MRI scan at 30 weeks' GA. Although no serious adverse events occurred and vital parameters remained stable during the procedure, minor adverse events were encountered in 26 infants (50%). The MRI was terminated in three infants (5.8%) because of respiratory instability. Increased respiratory support within 24 h after the MRI was necessary for 12 infants (23.1%) and was significantly associated with GA, birth weight and the mode of respiratory support. Hypothermia (core temperature < 36°C) occurred in nine infants (17.3%). Temperature dropped significantly after the MRI scan.
Minor adverse events after MRI procedures at 30 weeks GA were common and should not be underestimated. A dedicated and comprehensive guideline for MRI procedures in preterm infants is essential.
在相当于胎龄 30 周的足月时对早产儿进行脑部 MRI 检查已成为标准临床护理的一部分。
评估这些早期 MRI 检查的安全性。
我们回顾性收集了在进行早期 MRI 扫描的早产儿的患者安全性数据。在 MRI 扫描前后的固定时间收集数据。MRI 检查按照综合指南进行。
共有 52 名婴儿在 30 周 GA 时进行了 MRI 扫描。尽管在检查过程中没有发生严重不良事件且生命体征保持稳定，但仍有 26 名婴儿（50%）发生了轻微不良事件。由于呼吸不稳定，3 名婴儿（5.8%）的 MRI 检查被终止。12 名婴儿（23.1%）在 MRI 后 24 小时内需要增加呼吸支持，这与 GA、出生体重和呼吸支持方式显著相关。9 名婴儿（17.3%）出现低体温（核心温度<36°C）。MRI 扫描后体温明显下降。
30 周 GA 时 MRI 检查后的轻微不良事件很常见，不应被低估。对于早产儿的 MRI 检查，制定专门且全面的指南至关重要。
