Lukácsi K, Molnár M, Siroki O, Rosztóczy I
Acta Microbiol Hung. 1985;32(4):357-62.
Amantadine (greater than or equal to 100 micrograms/ml) treatment of chicken or human trachea organ cultures 6 h before infection inhibited influenza virus replication. Chicken or human leukocyte IFN evoked antiviral resistance in the cells of the homologous organ cultures only at a concentration of 100 U/ml or more. Treatment of organ cultures with combinations of the two substances resulted in an additive effect on influenza virus replication in both chicken and human tissues.
在感染前6小时用金刚烷胺（大于或等于100微克/毫升）处理鸡或人的气管器官培养物可抑制流感病毒复制。鸡或人白细胞干扰素仅在浓度为100 U/ml或更高时才能在同源器官培养物的细胞中引发抗病毒抗性。用这两种物质的组合处理器官培养物对鸡和人组织中的流感病毒复制均产生相加效应。
