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全美范围内,对美国手术中阿片类药物处方模式、趋势和系统水平预测因素的县一级分析:社会决定因素和获得心理健康服务很重要。

Nationwide, County-Level Analysis of the Patterns, Trends, and System-Level Predictors of Opioid Prescribing in Surgery in the US: Social Determinants and Access to Mental Health Services Matter.

机构信息

From the Division of Trauma, Emergency Surgery and Surgical Critical Care, Massachusetts General Hospital, Boston, MA (Gaitanidis, Dorken Gallastegi, Van Erp, Gebran, Velmahos, Kaafarani).

Department of Trauma Surgery, Leiden University Medical Center, Leiden, The Netherlands (Van Erp).

出版信息

J Am Coll Surg. 2024 Mar 1;238(3):280-288. doi: 10.1097/XCS.0000000000000920. Epub 2024 Jan 16.

Abstract

BACKGROUND

The diversion of unused opioid prescription pills to the community at large contributes to the opioid epidemic in the US. In this county-level population-based study, we aimed to examine the US surgeons' opioid prescription patterns, trends, and system-level predictors in the peak years of the opioid epidemic.

STUDY DESIGN

Using the Medicare Part D database (2013 to 2017), the mean number of opioid prescriptions per beneficiary (OPBs) was determined for each US county. Opioid-prescribing patterns were compared across counties. Multivariable linear regression was performed to determine relationships between county-level social determinants of health (demographic, eg median age and education level; socioeconomic, eg median income; population health status, eg percentage of current smokers; healthcare quality, eg rate of preventable hospital stays; and healthcare access, eg healthcare costs) and OPBs.

RESULTS

Opioid prescription data were available for 1,969 of 3,006 (65.5%) US counties, and opioid-related deaths were recorded in 1,384 of 3,006 counties (46%). Nationwide, the mean OPBs decreased from 1.08 ± 0.61 in 2013 to 0.87 ± 0.55 in 2017; 81.6% of the counties showed the decreasing trend. County-level multivariable analyses showed that lower median population age, higher percentages of bachelor's degree holders, higher percentages of adults reporting insufficient sleep, higher healthcare costs, fewer mental health providers, and higher percentages of uninsured adults are associated with higher OPBs.

CONCLUSIONS

Opioid prescribing by surgeons decreased between 2013 and 2017. A county's suboptimal access to healthcare in general and mental health services in specific may be associated with more opioid prescribing after surgery.

摘要

背景

未使用的阿片类药物处方在社区中的滥用是美国阿片类药物泛滥的原因之一。在这项以县为基础的人群研究中,我们旨在研究美国外科医生在阿片类药物泛滥高峰期的阿片类药物处方模式、趋势和系统水平预测因素。

研究设计

利用医疗保险处方数据库(2013 年至 2017 年),确定了每个美国县的每位受益人的阿片类药物处方平均数(OPB)。比较了各县之间的阿片类药物处方模式。采用多元线性回归分析方法,确定了县一级社会决定因素(人口统计学,如平均年龄和教育水平;社会经济,如平均收入;人口健康状况,如当前吸烟者比例;医疗保健质量,如可预防的住院率;以及医疗保健可及性,如医疗保健费用)与 OPB 之间的关系。

结果

1969 个美国县(65.5%)中有 1384 个县(46%)有阿片类药物相关死亡记录,可获得阿片类药物处方数据。全国范围内,OPB 从 2013 年的 1.08±0.61 降至 2017 年的 0.87±0.55;81.6%的县呈下降趋势。县一级的多变量分析显示,较低的人口平均年龄、较高的学士学位持有者比例、较高的报告睡眠不足的成年人比例、较高的医疗保健费用、较少的心理健康提供者以及较高的未参保成年人比例与较高的 OPB 相关。

结论

2013 年至 2017 年间,外科医生开具的阿片类药物处方数量有所减少。一般来说,一个县的医疗保健,特别是心理健康服务的获得情况较差,可能与手术后开具更多的阿片类药物处方有关。

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