Uniformed Services University of the Health Sciences.
Epidemiology and Analysis Branch, Armed Forces Health Surveillance Division, Defense Health Agency.
MSMR. 2024 Jan 20;31(1):2-8.
This report describes ivermectin prescription fill rates among U.S. active component service members (ACSM) over time during the early phases of the COVID-19 pandemic. Information about the unsubstantiated benefits of ivermectin for coronavirus 2019 (COVID-19) prevention and treatment was widely available online early in the COVID-19 pandemic. Ivermectin prescription fill rates increased among ACSM during periods of Alpha and Delta coronavirus variant predominance, but not during the predominance of the Omicron variant. At the peak of the fill rate curve, in August 2021, rates were higher among men compared to women, older compared to younger age groups, senior officers compared to junior officers, senior enlisted compared to junior enlisted service members, and those with a bachelor's or advanced degree compared to those without a bachelor's degree. Ivermectin prescriptions were more likely to have been filled at a retail pharmacy than at a military hospital or clinic. During the COVID-19 pandemic fill rates for ivermectin prescriptions among ACSM increased, including those without a qualifying diagnosis. Rates peaked in August 2021 but subsequently declined. The decrease in ivermectin fill rates was coincident with vigorous efforts to correct previous misinformation and implement pre-authorization requirements for prescriptions. Research on the impact of unproven online claims about clinical and public health interventions has potential to curtail future unnecessary and potentially harmful treatments.
本报告描述了在 COVID-19 大流行早期，美国现役军人（ACSM）中伊维菌素处方配药率随时间的变化情况。有关伊维菌素对 2019 年冠状病毒（COVID-19）预防和治疗的未经证实的益处的信息在 COVID-19 大流行早期就在网上广泛传播。在 Alpha 和 Delta 冠状病毒变体占主导地位期间，ACSM 中的伊维菌素处方配药率增加，但在 Omicron 变体占主导地位期间并未增加。在配药率曲线的峰值，即 2021 年 8 月，男性的配药率高于女性，年龄较大的人群高于年龄较小的人群，高级军官高于初级军官，高级 enlisted 人员高于初级 enlisted 人员，拥有学士或高级学位的人员高于没有学士学位的人员。伊维菌素处方更有可能在零售药店而不是在军队医院或诊所配药。在 COVID-19 大流行期间，ACSM 中伊维菌素处方的配药率增加，包括没有合格诊断的人。配药率在 2021 年 8 月达到峰值，但随后下降。伊维菌素配药率的下降与纠正先前错误信息和实施处方预授权要求的努力同时发生。对未经证实的有关临床和公共卫生干预措施的在线说法的影响进行研究，有可能遏制未来不必要和潜在有害的治疗方法。
