Crosby J H, Hoøeg K, Hager B
Diagn Cytopathol. 1985 Jul-Sep;1(3):221-7. doi: 10.1002/dc.2840010310.
Sarcomas, excluding lymphomas, are relatively uncommon targets of transthoracic fine needle aspiration. This paper presents a series of 11 adult patients with a variety of histologically documented sarcomas that were positive on transthoracic fine needle aspiration. Most tumors were metastatic from extrathoracic primary sites. We summarize the cytologic appearances of the aspirates and the clinical roles of fine needle aspiration in this setting. The aspirates resembled the corresponding histologic sections in cellular morphology. Nine different histologic types of sarcomas therefore produced a wide variety of cytologic appearances. Two findings, though not specific for sarcomas, were common and are suggested as clues to the recognition of sarcomas: (1) poor cohesion of cells and (2) numerous spindle cells. Transthoracic fine needle aspiration confirmed a strongly suspected clinical diagnosis in 7 cases, and it clarified a more obscure clinical diagnosis in 4 cases. Suggestions are presented for differential diagnosis.
除淋巴瘤外，肉瘤是经胸细针穿刺活检相对罕见的目标。本文报告了11例成年患者，他们患有各种组织学确诊的肉瘤，经胸细针穿刺活检结果呈阳性。大多数肿瘤是胸外原发部位转移而来。我们总结了穿刺抽吸物的细胞学表现以及在此情况下细针穿刺活检的临床作用。穿刺抽吸物在细胞形态上与相应的组织学切片相似。因此，9种不同组织学类型的肉瘤产生了各种各样的细胞学表现。有两个发现虽然并非肉瘤所特有，但很常见，可作为识别肉瘤的线索：（1）细胞黏附性差；（2）大量梭形细胞。经胸细针穿刺活检在7例中证实了高度怀疑的临床诊断，在4例中明确了更模糊的临床诊断。本文还提出了鉴别诊断的建议。
