Inuganti Renuka V, Bala Saila G, Bharathi Krishna Y
Department of Pathology, Guntur Medical College, Guntur, Andhra Pradesh - 522 004, India.
J Cytol. 2011 Jan;28(1):33-5. doi: 10.4103/0970-9371.76948.
Myxoid liposarcomas metastatic to lungs and mediastinum are infrequent lung neoplasms. The tumor has an aggressive course and needs to be recognized cytologically. A 60-year-old male smoker presented with gradually progressive left-sided chest pain, cough, and expectoration for the past one month. Chest radiograph and computed tomography of thorax revealed a lung mass in left apical region extending into the posterior mediastinum, which was subjected to ultrasound-guided fine needle aspiration (FNA). Smears showed a cellular tumor with ovoid to spindle shaped tumor cells in a myxoid background having a rich vascular network. The possibility of a myxoid liposarcoma metastatic to lung and mediastinum was suggested and confirmed by histopathology. A previous history of excision of a tumor in the thigh one and half years ago was present. The importance of recognizing the cytological picture by FNA is discussed.
转移至肺和纵隔的黏液样脂肪肉瘤是一种罕见的肺部肿瘤。该肿瘤病程进展迅速,需要通过细胞学检查来识别。一名60岁男性吸烟者,在过去一个月中出现逐渐加重的左侧胸痛、咳嗽和咳痰症状。胸部X线片和胸部计算机断层扫描显示左肺尖部有一肿块,延伸至后纵隔,对其进行了超声引导下细针穿刺抽吸(FNA)。涂片显示为细胞性肿瘤,在富含血管网络的黏液样背景中可见卵圆形至梭形的肿瘤细胞。提示为转移至肺和纵隔的黏液样脂肪肉瘤,并经组织病理学证实。患者有一年半前大腿部肿瘤切除史。文中讨论了通过FNA识别细胞学表现的重要性。