新型冠状病毒肺炎重症监护病房幸存者的健康相关生活质量及其决定因素评估
Assessment of health-related quality of life and its determinants among COVID-19 intensive care unit survivors.
作者信息
Neelima Mariyala, Chivukula Satya K
机构信息
Department of Community Medicine, Dr Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Chinnaavutapalli, Gannavaram, Andhra Pradesh, India.
Department of Community Medicine, Government Siddhartha Medical College, Vijayawada, Andhra Pradesh, India.
出版信息
J Family Med Prim Care. 2023 Dec;12(12):3319-3325. doi: 10.4103/jfmpc.jfmpc_739_23. Epub 2023 Dec 21.
BACKGROUND
Health-related quality of life (HRQoL) is a multidimensional concept encompassing the physical, functional, emotional, and social/family well-being of an individual. Recent reports suggest that Covid-19 may lead to poorer HRQoL of the patients infected both in the short and long term. The present study aimed to assess the health-related quality of life and their determinants among COVID-19 intensive care unit (ICU) survivors.
MATERIALS AND METHODS
In the study, 107 COVID-19 (RTPCR positive) patients admitted to the (ICU) of a tertiary care centre from August 2021-January 2022 were taken from the hospital records. Line listing of all the patients was done, and the study population was selected using the lottery method under a simple random sampling method. The study population was contacted by telephone and requested their willingness to participate in the study. EQ-5D-5L was used to assess quality of life, which is a standard instrument to assess HRQoL (developed by the EuroQol group in 2011). The EQ-5D-5L essentially consists of the EQ-5D descriptive system and the EQ visual analogue scale (EQ-VAS). Data entry was done using Microsoft excel 2019 version and data analysis using MedCalc version 20.015.
RESULTS
The mean EQ-5D-5L utility score was 0.51 ± 0.43. The mean EQ-VAS score was 68.97 ± 22.27. A significant association between co-morbidities and EQ-5D-5L utility score where those with co-morbidities had a lesser EQ-5D-5L score compared to those without co-morbidities. The mean duration of ICU stay in days was 12.29 ± 12.17. A significant negative correlation between the duration of ICU stay and EQ-5D-5L. (r = -0.26, = 0.0006*).
CONCLUSION
COVID-19 patients with comorbidities had a significantly poor quality of life. These findings may help healthcare professionals and decision-makers to better understand the consequences of COVID-19 on the HRQoL.
背景
健康相关生活质量(HRQoL)是一个多维概念,涵盖个人的身体、功能、情感以及社会/家庭幸福感。近期报告表明,新冠病毒病(Covid-19)可能在短期和长期内导致感染患者的健康相关生活质量下降。本研究旨在评估新冠病毒病重症监护病房(ICU)幸存者的健康相关生活质量及其决定因素。
材料与方法
在本研究中,从一家三级医疗中心2021年8月至2022年1月入住ICU的107例新冠病毒病(逆转录聚合酶链式反应检测呈阳性)患者的医院记录中选取研究对象。对所有患者进行了一览表登记,并采用简单随机抽样法中的抽签法选取研究人群。通过电话联系研究人群,询问他们参与研究的意愿。使用EQ-5D-5L评估生活质量,这是一种评估健康相关生活质量的标准工具(由欧洲生活质量研究组于2011年开发)。EQ-5D-5L主要由EQ-5D描述系统和EQ视觉模拟量表(EQ-VAS)组成。使用Microsoft excel 2019版本进行数据录入,使用MedCalc 20.015版本进行数据分析。
结果
EQ-5D-5L效用得分的平均值为0.51±0.43。EQ-VAS得分的平均值为68.97±22.27。合并症与EQ-5D-5L效用得分之间存在显著关联,合并症患者的EQ-5D-5L得分低于无合并症患者。ICU住院天数的平均值为12.29±12.17。ICU住院时间与EQ-5D-5L之间存在显著负相关(r = -0.26,P = 0.0006*)。
结论
合并症的新冠病毒病患者生活质量明显较差。这些发现可能有助于医疗保健专业人员和决策者更好地了解新冠病毒病对健康相关生活质量的影响。