Zeng Yuan, Liu Hui, Cui Fei, Cai Weipeng, He Jianxing, Liu Jun
Department of Thoracic Surgery & Department of Organ Transplantation, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Guangzhou Institute of Respiratory Disease & China State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou, China.
MethodsX. 2024 Feb 6;12:102607. doi: 10.1016/j.mex.2024.102607. eCollection 2024 Jun.
While spontaneous ventilation (SV) anesthesia is in use for clinical patients, there is still little systematic experimental research into its basic aspects. The rabbit SV model that we established previously has some limitations including the model being too small, differences in anesthetic drugs and anesthesia procedures, so we set out to establish an SV anesthesia model for beagle dogs.•Single lumen tracheal intubation was performed on beagles connecting a ventilator, and the anesthetic dosage was adjusted for spontaneous ventilation before surgery.•5 mL of 1 % lidocaine was applied as a local infiltration anesthesia at the surgical incision.•After thoracotomy, 5 mL of 1% lidocaine was sprayed onto the surface of the lungs and a T3-T7 intercostal nerve block (1:1 2 % lidocaine:0.75 % ropivacaine) was performed.
在临床患者使用自主通气(SV)麻醉时,对其基本方面仍缺乏系统的实验研究。我们之前建立的兔SV模型存在一些局限性,包括模型过小、麻醉药物和麻醉程序存在差异,因此我们着手为比格犬建立SV麻醉模型。
• 对比格犬进行单腔气管插管并连接呼吸机,术前调整麻醉剂量以实现自主通气。
• 在手术切口处应用5 mL 1%利多卡因进行局部浸润麻醉。
• 开胸后,将5 mL 1%利多卡因喷洒在肺表面,并进行T3-T7肋间神经阻滞(1:1 2%利多卡因:0.75%罗哌卡因)。