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芬太尼透皮贴剂临床合理使用指南。

Guidelines for Rational Clinical Use of Fentanyl Transdermal Patch.

机构信息

Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China.

Cancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, People's Republic of China.

出版信息

Drug Des Devel Ther. 2024 Feb 1;18:233-255. doi: 10.2147/DDDT.S414318. eCollection 2024.

Abstract

Pain is one of the most common clinical symptoms of cancer patients, seriously affecting the quality of life of patients and bringing heavy mental and economic burden to families and society. The treatment of cancer pain in China is facing numerous challenges, one of which includes the irrational usage of analgesic drugs in clinical practice. As a strong opioid analgesic, transdermal fentanyl patch has been widely used due to its convenient clinical application and obvious therapeutic effect. Several basic-level hospitals and even general hospitals in China fail to appropriate the application of drugs in clinical application due to the lack of understanding of the pharmacological characteristics and clinical application of fentanyl transdermal patch by medical staff, seriously affecting the treatment quality. Therefore, it is imperative to strengthen the rational use and management of fentanyl transdermal patches. Accordingly, the initiation by the Cancer Rehabilitation and Palliative Treatment Professional Committee of the Hubei Anti-cancer Association launched the compilation of the "Guidelines for Rational Clinical Use of Fentanyl Transdermal Patch" (from now on referred to as the "Guidelines") in Hubei Province, China. The experts in the preparation group are experts in many disciplines, such as medicine, pharmacy, and nursing. The expert group determines the outline, prepares the required regulations, and revises it repeatedly. Moreover, these experts put forward suggestions for revision to strictly control the accuracy and scientific authenticity of the contents of the "Guide". Finally, all experts of the preparation team certify and finalize the draft. This "Guide" prepared by experts of the Cancer Rehabilitation and Palliative Treatment Professional Committee of the Hubei Anti-cancer Association and the expert advisory group with joint efforts, aims to play a positive role in promoting the rational clinical use of fentanyl transdermal patch, reducing the mental and economic burden of patients, and ensuring medical quality and medical safety.

摘要

疼痛是癌症患者最常见的临床症状之一,严重影响患者的生活质量,并给家庭和社会带来沉重的精神和经济负担。中国癌症疼痛的治疗面临诸多挑战,其中之一是临床实践中镇痛药的不合理使用。芬太尼透皮贴剂作为一种强阿片类镇痛药,因其临床应用方便、疗效确切而被广泛应用。由于医务人员对芬太尼透皮贴剂的药理学特点和临床应用缺乏了解,中国一些基层医院甚至综合医院在临床应用中未能合理应用药物,严重影响了治疗质量。因此,加强芬太尼透皮贴剂的合理使用和管理势在必行。为此,湖北省抗癌协会癌症康复与姑息治疗专业委员会启动了《芬太尼透皮贴剂临床合理使用指南》(以下简称《指南》)的编写工作。编写组成员均为医学、药学、护理等多学科专家。专家组确定大纲,编写所需规范,并反复修订。此外,这些专家还提出了修订建议,严格控制《指南》内容的准确性和科学性。最后,编写组全体专家对草案进行了审定和定稿。本《指南》由湖北省抗癌协会癌症康复与姑息治疗专业委员会专家和专家咨询组共同编写,旨在积极促进芬太尼透皮贴剂的合理临床应用,减轻患者的精神和经济负担,保障医疗质量和医疗安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12a8/10869233/3b5c690014fb/DDDT-18-233-g0001.jpg

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