Park Kyung Nam, Karm Myong-Hwan, Seo Kwang-Suk, Kim Hyun Jeong, Ryoo Seung-Hwa
Department of Dental Anesthesiology, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
J Dent Anesth Pain Med. 2024 Feb;24(1):75-80. doi: 10.17245/jdapm.2024.24.1.75. Epub 2024 Feb 1.
Dental sedation plays a pivotal role in alleviating patient anxiety during various procedures. Remimazolam, a benzodiazepine derivative, stands out for its distinctive attributes, particularly its rapid onset of sedation coupled with a brief duration, making it an invaluable option for dental applications. The patient was admitted for the extraction of impacted third molars via patient-controlled sedation and not only demonstrated stable vital signs but also expressed a high level of satisfaction with the procedure. An in-depth analysis of plasma remimazolam concentrations and changes in the Patient State Index revealed negative correlation patterns, highlighting the inherent potential of remimazolam in achieving effective sedation. This expanded research scope aims to provide a more nuanced understanding of the pharmacological responses to remimazolam in dental sedation scenarios. This case report offers valuable insights into the evolving landscape of dental sedation methodologies and paves the way for a more informed and evidence-based approach to the use of remimazolam in patient-controlled sedation.
牙科镇静在减轻患者在各种手术过程中的焦虑方面起着关键作用。瑞马唑仑是一种苯二氮䓬衍生物,因其独特的特性而脱颖而出,特别是其起效迅速且持续时间短,使其成为牙科应用中非常有价值的选择。该患者因通过患者自控镇静进行阻生第三磨牙拔除术而入院,不仅生命体征稳定,而且对手术表示高度满意。对血浆瑞马唑仑浓度和患者状态指数变化的深入分析揭示了负相关模式,突出了瑞马唑仑在实现有效镇静方面的内在潜力。这一扩大的研究范围旨在更细致地了解牙科镇静场景中对瑞马唑仑的药理反应。本病例报告为牙科镇静方法的不断发展提供了宝贵的见解,并为在患者自控镇静中更明智、基于证据地使用瑞马唑仑铺平了道路。