Department of Dental Surgery and Oral Health Sciences, AFMC.
Department of Pathology, AFMC, Pune, Maharashtra, India.
J Craniofac Surg. 2024 Jun 1;35(4):e321-e325. doi: 10.1097/SCS.0000000000010021. Epub 2024 Feb 16.
Plasmablastic lymphoma (PBL) is an uncommon and aggressive large B-cell lymphoma commonly diagnosed in human immunodeficiency virus-positive patients. Though the oral cavity is a common site for PBL, this condition is not commonly reported in the literature as an oral manifestation. Most oral PBLs presented as an asymptomatic swelling, frequently associated with ulcerations and bleeding. No standard treatment is yet advocated for oral PBL. Five-year survival rate was recorded not more than 33.5%. This presentation emphasizes on oral manifestation of plasmablastic lymphoma (PBL) as a rare entity, which was provisionally diagnosed for carcinoma (CA) oral cavity. A simple presentation of ulcerated growth in the upper jaw was excised for histopathologic evaluation. Subsequently, it turned out to be a rare oral manifestation of HIV-related lymphoma. It is imperative to understand simple oral presentation as a manifestation of an underlying systemic condition. With this interest, this case presentation is published with a literature review.
弥漫性大 B 细胞淋巴瘤（DLBCL）是一种常见的侵袭性非霍奇金淋巴瘤，常见于人类免疫缺陷病毒（HIV）阳性患者。尽管口腔是弥漫性大 B 细胞淋巴瘤的常见部位，但文献中很少有将其作为口腔表现的报道。大多数口腔弥漫性大 B 细胞淋巴瘤表现为无症状肿胀，常伴有溃疡和出血。目前尚无针对口腔弥漫性大 B 细胞淋巴瘤的标准治疗方法。5 年生存率记录不超过 33.5%。本病例强调了口腔弥漫性大 B 细胞淋巴瘤（PBL）作为一种罕见实体的口腔表现，最初被诊断为口腔癌（CA）。为了进行组织病理学评估，对上颌的溃疡性生长物进行了简单切除。随后，结果显示为与 HIV 相关的淋巴瘤的一种罕见口腔表现。了解简单的口腔表现是潜在系统性疾病的一种表现形式是至关重要的。基于这一兴趣，本病例报告结合文献复习进行发表。
