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孤立性卵巢浆细胞瘤:关于一种罕见的髓外浆细胞肿瘤实体。

Solitary ovarian plasmacytoma: About a rare entity of extramedullary plasma cell tumor.

作者信息

El Abbassi Imane, ElHodaigui N, Boufettal H, Mahdaoui S, Samouh N

机构信息

Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

出版信息

Int J Surg Case Rep. 2024 Mar;116:109096. doi: 10.1016/j.ijscr.2023.109096. Epub 2023 Dec 2.

Abstract

INTRODUCTION

Solitary ovarian plasmacytoma is a rare form of extramedullary plasmacytic tumor that develops outside the bone marrow.

PRESENTATION OF CASE

We report the case of a 52-year-old female patient who consulted for pelvic pain and abdominal distension. Clinical examination revealed an abdominopelvic mass and a pelvic MRI confirmed a right ovarian mass. The diagnosis of ovarian plasmacytoma was made after exploratory laparotomy.

DISCUSSION

Extramedullary plasmacytoma (EMP) is rare and most often found in the upper aerodigestive tract, ovarian localization is exceptional. Histological and immunohistochemical features of EMP highlights similarities with multiple myeloma. EMP treatment options are discussed, including radiotherapy, surgery, and chemotherapy. The prognosis of EMP depends on several factors, including tumor size and timing of treatment.

CONCLUSION

Solitary ovarian plasmacytoma is a rare but important entity to consider in the diagnosis of abdominopelvic masses. Appropriate treatment, such as surgery combined with radiotherapy, can be effective, although regular monitoring is necessary due to the risk of relapse and transformation into multiple myeloma.

摘要

引言

孤立性卵巢浆细胞瘤是一种罕见的骨髓外浆细胞性肿瘤,发生于骨髓外。

病例介绍

我们报告一例52岁女性患者,因盆腔疼痛和腹胀前来就诊。临床检查发现腹盆腔肿块,盆腔磁共振成像(MRI)证实右侧卵巢有肿块。经剖腹探查术后确诊为卵巢浆细胞瘤。

讨论

骨髓外浆细胞瘤(EMP)罕见,最常见于上呼吸消化道,卵巢部位的EMP极为罕见。EMP的组织学和免疫组化特征显示与多发性骨髓瘤相似。文中讨论了EMP的治疗选择,包括放疗、手术和化疗。EMP的预后取决于多个因素,包括肿瘤大小和治疗时机。

结论

孤立性卵巢浆细胞瘤虽罕见,但在腹盆腔肿块的诊断中是一个需要考虑的重要疾病。适当的治疗,如手术联合放疗,可能有效,不过由于存在复发及转化为多发性骨髓瘤的风险,仍需定期监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af93/10943662/9692f3421db0/gr1.jpg

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