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西班牙医院狼疮的发病率和医疗费用:一项回顾性数据库分析。

Incidence and medical costs of lupus in Spanish hospitals: a retrospective database analysis.

机构信息

Department of Economics, University of Barcelona, Diagonal 690, 08034, Barcelona, Spain.

BCN Health Economics & Outcomes Research S.L., Travessera de Gràcia, 62, 08006, Barcelona, Spain.

出版信息

Orphanet J Rare Dis. 2024 Feb 16;19(1):74. doi: 10.1186/s13023-024-03077-1.

Abstract

BACKGROUND

This study aimed to assess the comorbidity profile, use of healthcare resources and medical costs of patients with systemic lupus erythematosus (SLE) and cutaneous lupus erythematosus (CLE) treated at the hospital level in Spain.

METHODS

Admission records of patients with SLE and CLE that were registered between January 2016 and December 2020 were obtained from a Spanish hospital discharge database and analyzed in a retrospective multicenter study.

RESULTS

329 patients met the criteria; 64.44% were female and 35.56% were male, with a median age of 54.65 years. Mean Charlson comorbidity index (CCI) was 2.75 in the index admission. 31.61% of the patients suffered essential hypertension, 21.96% suffered asthma and 19.76% suffered hyperlipidemia. Mortality rate was 3.95%. The most common medical procedure was heart ultrasound (19.45%) and introduction in peripheral vein of anti-inflammatory with a percutaneous approach (17.93%). Mean admission cost was €6355.99.

CONCLUSIONS

Lupus patients showed a higher incidence and prevalence in the female population, with associated cardiac diseases as the main secondary conditions.

摘要

背景

本研究旨在评估在西班牙医院治疗的系统性红斑狼疮(SLE)和皮肤红斑狼疮(CLE)患者的合并症谱、医疗资源利用和医疗费用。

方法

从一家西班牙医院出院数据库中获取了 2016 年 1 月至 2020 年 12 月期间登记的 SLE 和 CLE 患者的入院记录,并进行了回顾性多中心研究分析。

结果

329 名患者符合标准;64.44%为女性,35.56%为男性,中位年龄为 54.65 岁。指数入院时平均 Charlson 合并症指数(CCI)为 2.75。31.61%的患者患有原发性高血压,21.96%患有哮喘,19.76%患有高血脂症。死亡率为 3.95%。最常见的医疗程序是心脏超声(19.45%)和经皮外周静脉注射抗炎药物(17.93%)。平均入院费用为 6355.99 欧元。

结论

狼疮患者在女性人群中发病率和患病率较高,主要的次要疾病是心脏病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01aa/10874055/8582a8f8ea20/13023_2024_3077_Fig1_HTML.jpg

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