Poungshompoo S
Acta Vet Scand. 1985;26(4):549-62. doi: 10.1186/BF03546526.
In 19 out of 22 aortas from fallow deer, 15 months to 5½ years, aortic lesions were found. Three types of lesions were observed, fatty streaks were seen in 2, fibrous plaques in 15 and fibrous plaques with complicated lesions (calcification and acid mucopolysaccharides) in 2 of the aortas. Elastic tissue degeneration of the inner two thirds of the tunica media was frequently found in the aorta of the animals > 3½–5½ years of age. There was no statistical evidence for a correlation between age and frequency (P ~ 0.10) but a trend towards age dependence was seen. The percentage of involved surface was found to significantly increase (0.05 > P > 0.01) with age. Lesions were found to start in the abdominal aorta in young animals and to extend cranially to the thoracic aorta with age. The percentage of involved surface in different affected regions, comprising all age groups were, in the posterior abdominal portion, 10.5 %, in the anterior abdominal portion, 4.3 % and in the posterior thoracic portion, 1.04 %. The influence of hemodynamic flow upon the localization of the aortic lesions, the endothelial cell population density and the endothelial nuclear patterns were discussed.
在22只15个月至5.5岁的黇鹿主动脉中，有19只发现了主动脉病变。观察到三种类型的病变，2只主动脉出现脂肪条纹，15只出现纤维斑块，2只出现伴有复杂病变（钙化和酸性粘多糖）的纤维斑块。在年龄大于3.5至5.5岁的动物主动脉中，经常发现中膜内三分之二的弹性组织变性。年龄与病变频率之间没有统计学上的相关性证据（P约为0.10），但存在年龄依赖性趋势。发现受累表面的百分比随年龄显著增加（0.05＞P＞0.01）。病变在幼龄动物中始于腹主动脉，并随着年龄增长向头侧延伸至胸主动脉。在所有年龄组中，不同受累区域的受累表面百分比分别为：腹主动脉后部10.5%，腹主动脉前部4.3%，胸主动脉后部1.04%。讨论了血流动力学对主动脉病变定位、内皮细胞群体密度和内皮细胞核形态的影响。
