头颈部癌患者的多原发性肿瘤

Multiple primary tumors in patients with head and neck cancer.

作者信息

Miyahara H, Tsuruta Y, Umatani K, Yoshino K, Sato T

出版信息

Auris Nasus Larynx. 1985;12 Suppl 2:S30-5. doi: 10.1016/s0385-8146(85)80024-9.

Abstract

From July 1978 to June 1984, 851 new cases of malignancies in the head and neck were registered in our hospital. Ninety-three patients with multiple primary tumors were observed. Triplicated malignancies were observed in three cases, i.e., larynx, thyroid, skin; stomach, tongue, larynx; and larynx, sarcoma, mesopharynx. The incidence rate was a high 30% in cancer of the mesopharynx (14/46), 14% in cancer of the larynx (55/392), and 7% in cancer of the hypopharynx. Additional primary malignancies occurred in the head and neck regions (25 cases), the digestive system (10 cases), the uro-reproductive system (18 cases), and others. Cancers of the stomach, lung, esophagus, and thyroid were predominant. Thirty-one cases (32.2%) were detected simultaneously and others were detected synchronously. We discuss the increased incidence rate of multiple primary tumors and the factors attributable to multiple primary tumors and stress the usefulness of systematic investigations.

摘要

1978年7月至1984年6月，我院共登记851例头颈部恶性肿瘤新发病例。观察到93例多原发性肿瘤患者。3例出现三重恶性肿瘤，即喉、甲状腺、皮肤；胃、舌、喉；以及喉、肉瘤、下咽。下咽癌的发病率高达30%（14/46），喉癌为14%（55/392），下咽癌为7%。其他原发性恶性肿瘤发生在头颈部区域（25例）、消化系统（10例）、泌尿生殖系统（18例）等。胃癌、肺癌、食管癌和甲状腺癌最为常见。31例（32.2%）为同时检测到，其他为同步检测到。我们讨论了多原发性肿瘤发病率的增加以及多原发性肿瘤的相关因素，并强调了系统检查的有用性。