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将儿科头痛归入精神障碍?德尔菲分类学、诊断难题以及干预措施变异性的批判。

Subsume Pediatric Headaches in Psychiatric Disorders? Critiques on Delphic Nosology, Diagnostic Conundrums, and Variability in the Interventions.

机构信息

Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.

Department of Psychology, Christ University, Delhi, NCR, India.

出版信息

Curr Pain Headache Rep. 2024 Jul;28(7):651-662. doi: 10.1007/s11916-024-01225-7. Epub 2024 Feb 17.

Abstract

PURPOSE OF REVIEW

Tension-type headache (TTH) continues to be the most prevalent type of headache across all age groups worldwide, and the global burden of migraine and TTH together account for 7% of all-cause years lived with disability (YLDs). TTH has been shown to have a prevalence of up to 80% in several studies and presents a wide range and high variability in clinical settings. The aim of this review is to identify gaps in diagnostics, nosology, and variability in the treatment of children and adolescents who present with headaches without an identifiable etiology.

RECENT FINDINGS

Migraine and TTH have been debated to have more similarities than distinctions, increasing chances of misdiagnosis and leading to significant cases diagnosed as probable TTH or probable migraine. The lack of specificity and sensitivity for TTH classification often leads to the diagnosis being made by negating associated migraine symptoms. Although pathology is not well understood, some studies have suggested a neurological basis for TTH, in need of further validation. Some research indicates that nitric oxide signaling plays an integral part in the pain mechanisms related to TTH. Analgesics and non-steroidal anti-inflammatories are usually the first lines of treatment for children with recurring headaches, and additional treatment options include medication and behavioral therapies. With high prevalence and socioeconomic burden among children and adolescents, it's essential to further study Tension-type headaches and secondary headaches without known cause and potential interventions. Treatment studies involving randomized controlled trials are also needed to test the efficacy of various treatments further.

摘要

综述目的

紧张型头痛(TTH)仍然是全球所有年龄段最常见的头痛类型,偏头痛和 TTH 一起占所有致残年数(YLDs)的 7%。几项研究表明 TTH 的患病率高达 80%,在临床环境中表现出广泛的范围和高度的可变性。本综述的目的是确定在诊断、分类学和治疗方面存在的差距,这些儿童和青少年表现出无明显病因的头痛。

最新发现

偏头痛和 TTH 被认为具有更多的相似之处而不是区别,这增加了误诊的机会,并导致大量被诊断为可能 TTH 或可能偏头痛的病例。TTH 分类的特异性和敏感性不足,往往导致通过否定相关的偏头痛症状来做出诊断。尽管病理机制尚不清楚,但一些研究表明 TTH 具有神经学基础,这需要进一步验证。一些研究表明,一氧化氮信号在与 TTH 相关的疼痛机制中起着重要作用。对于经常头痛的儿童,通常使用镇痛药和非甾体抗炎药作为一线治疗,其他治疗选择包括药物治疗和行为疗法。由于儿童和青少年的患病率和社会经济负担较高,因此进一步研究无明显原因的 TTH 和继发性头痛以及潜在的干预措施至关重要。还需要涉及随机对照试验的治疗研究来进一步测试各种治疗方法的疗效。

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