Digoutte J P, Saluzzo J F, Adam F
Bull Soc Pathol Exot Filiales. 1985;78(5 Pt 2):874-8.
Among the viruses which can provoke human haemorrhagic fevers, the Congo-Crimean Haemorrhagic Fever and Rift Valley Fever viruses have been discovered relatively recently in West Africa. Two human cases of severe haemorrhagic fever have been connected with Congo-CHF, in Mauritania and Burkina-Faso. The epidemiological enquiry performed in Mauritania, consequent to the appearance of the first case, has demonstrated that the patient had been contaminated by contact with camels. Twelve strains of Congo-CHF virus have been isolated from ticks taken on bovines and dromedaries in that area. The serological enquiries realized on man show that the incidence is relatively feeble; on the other hand, among animals, one finds a large distribution among small ruminants in Mauritania as well as in Senegal. The recent realization of a complete identity between the Zinga and Rift Valley Fever viruses has broadened the geographical distribution of this virus to the whole of inter-tropical Africa including Madagascar. The serological enquiries realized among men and animals in areas where the virus has been isolated from wild vectors show that the presence of antibodies is faintly superior. On the other hand, in southern Mauritania, the virus prevails among men, who get antibodies of the IGM type, which proves a recent circulation. The immunological enquiries on camels seem to corroborate these data. The Rift Valley Fever epidemic which broke out in 1978 among the human and animal populations of Egypt has, apparently, been connected with the passage of camels coming from Sudan through the intermediary halting-place of the Assuan dam.(ABSTRACT TRUNCATED AT 250 WORDS)
在能够引发人类出血热的病毒中,刚果-克里米亚出血热病毒和裂谷热病毒是最近在西非发现的。在毛里塔尼亚和布基纳法索,有两例严重出血热病例与刚果-克里米亚出血热有关。在毛里塔尼亚出现首例病例后进行的流行病学调查表明,该患者是通过与骆驼接触而被感染的。已从该地区牛和单峰骆驼身上采集的蜱中分离出12株刚果-克里米亚出血热病毒。对人类进行的血清学调查显示,发病率相对较低;另一方面,在动物中,在毛里塔尼亚以及塞内加尔的小反刍动物中发现了广泛分布。最近发现津加病毒和裂谷热病毒完全相同,这将该病毒的地理分布扩大到包括马达加斯加在内的整个热带非洲。在从野生传播媒介中分离出该病毒的地区对人和动物进行的血清学调查表明,抗体的存在略多一些。另一方面,在毛里塔尼亚南部,该病毒在人群中流行,人们产生免疫球蛋白M型抗体,这证明该病毒最近在传播。对骆驼的免疫学调查似乎证实了这些数据。1978年在埃及的人和动物中爆发的裂谷热疫情显然与来自苏丹的骆驼经阿斯旺大坝的中间停留地过境有关。(摘要截于250字)