Lee Yong Yi, Slade Tim, Chatterton Mary Lou, Le Long Khanh-Dao, Perez Joahna K, Faller Jan, Chapman Cath, Newton Nicola C, Sunderland Matthew, Teesson Maree, Mihalopoulos Cathrine
Monash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; School of Public Health, The University of Queensland, Brisbane, Australia; Queensland Centre for Mental Health Research, Brisbane, Australia.
The Matilda Centre for Research in Mental Health and Substance Use, The University of Sydney, Sydney, Australia.
Prev Med. 2024 Apr;181:107898. doi: 10.1016/j.ypmed.2024.107898. Epub 2024 Feb 15.
Public health guidelines recommend delaying the initiation age for alcohol. However, the causal link between age-at-first-drink (AFD) and future alcohol use in young adulthood is uncertain. This study examined the association between AFD and alcohol-related outcomes at age 20 years using an Australian sample.
Data were obtained from Waves 1-19 (years 2001-2019) of the Household, Income and Labour Dynamics in Australia Survey on 20-year-olds with responses across ≥3 consecutive waves (n = 2278). The AFD for each respondent (between 15 and 20 years) was analysed relative to Australian legal drinking age (18 years). Inverse probability treatment weighting was used to evaluate associations between AFD and four outcomes at age 20 years: risk of current alcohol use; quantity of weekly alcohol consumption; risk of binge drinking; and frequency of binge drinking. Adjustments were made for confounders (e.g., heavy drinking by parents). Robustness of study findings was evaluated using several diagnostic tests/sensitivity analyses.
Among 20-year-olds, those with an AFD of 15-16 years consumed significantly more alcohol per week compared to an AFD of 18 years. Additionally, 20-year-old drinkers with an AFD of 16 years were significantly more likely to binge drink (though this association was likely confounded). An inverse dose-response relationship was observed between AFD and weekly alcohol consumption at 20 years, where a higher AFD led to lower alcohol consumption.
Study findings indicate an association between a higher AFD and consuming less alcohol in young adulthood, which could potentially support the scale-up of prevention programs to delay AFD among Australian adolescents.
公共卫生指南建议推迟饮酒起始年龄。然而,首次饮酒年龄(AFD)与青年期未来饮酒之间的因果关系尚不确定。本研究使用澳大利亚样本,考察了AFD与20岁时酒精相关结局之间的关联。
数据来自澳大利亚家庭、收入与劳动力动态调查的第1 - 19波(2001 - 2019年),对象为20岁且连续至少回复3波的受访者(n = 2278)。分析每位受访者(15至20岁)的AFD相对于澳大利亚法定饮酒年龄(18岁)的情况。采用逆概率处理加权法评估AFD与20岁时四个结局之间的关联:当前饮酒风险;每周酒精消费量;暴饮风险;暴饮频率。对混杂因素(如父母酗酒)进行了调整。使用多种诊断测试/敏感性分析评估研究结果的稳健性。
在20岁人群中,AFD为15 - 16岁的人每周饮酒量显著多于AFD为18岁的人。此外,AFD为16岁的20岁饮酒者暴饮的可能性显著更高(尽管这种关联可能存在混杂)。在20岁时观察到AFD与每周酒精消费量之间存在反向剂量反应关系,即AFD越高,酒精消费量越低。
研究结果表明,较高的AFD与青年期饮酒量较少之间存在关联,这可能支持扩大预防项目规模,以推迟澳大利亚青少年的AFD。