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基层医疗中妊娠母亲因血红蛋白持续不变的先天性春血贫血导致铁过载。

Iron overload in anaemia with underlying haemoglobin constant spring in an antenatal mother in primary care.

机构信息

Family Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia

Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.

出版信息

BMJ Case Rep. 2024 Feb 17;17(2):e258526. doi: 10.1136/bcr-2023-258526.

Abstract

This is the case of a gravida 3 para 1 woman in her late 20s with underlying haemoglobin constant spring who visited a healthcare clinic for an antenatal check-up. Towards the end of her second trimester, she experienced lethargy. During her antenatal booking, she was diagnosed with mild asymptomatic anaemia, high serum ferritin, T saturation of 88% and abnormal liver function tests. She was referred to a hospital where an MRI scan revealed over 2 g of iron deposits in her liver, leading to a revised diagnosis of iron overload. Treatment included deferoxamine and expectant management throughout her antenatal period, and her delivery was uncomplicated. While iron deficiency anaemia is common in pregnancy, it is crucial not to overlook iron deposition and the distinction from acute fatty liver during pregnancy to prevent treatment delays.

摘要

这是一位 20 多岁、妊娠 3 次、产 1 次的血红蛋白持续春(Constant Spring)的女性患者,因产前检查就诊于医疗诊所。在妊娠中期末,她出现乏力。在产前预约时,她被诊断为轻度无症状性贫血、血清铁蛋白高、T 饱和度 88%和肝功能异常。她被转介到一家医院,磁共振成像(MRI)扫描显示她的肝脏有超过 2 克的铁沉积,导致重新诊断为铁过载。治疗包括在整个产前期间使用去铁胺和期待治疗,她的分娩过程顺利。虽然缺铁性贫血在妊娠中很常见,但必须注意铁沉积并与妊娠急性脂肪肝相区别,以避免治疗延误。

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