Song S T
Zhonghua Zhong Liu Za Zhi. 1985 Nov;7(6):426-9.
Estrogen receptor (ER) was measured in 275 samples from 170 patients with breast cancer by dextran-coated charcoal assay. The results showed that the ER positive rate was 51.2%. The ER status of female patients was not related to age or menopause. The positive rate was lowest in AB blood type. The distribution of positive patients in all types was similar to that reported by Japanese authors. The DNA levels of ER positive cancers were relatively lower than those of negative ones. Pathological examination of cancer tissue indicated that ER positive cancer is well differentiated. The 3 year disease-free rate and 4 year survival rate are both high in ER positive patients than that in the negative patients. Knowledge of ER status is helpful in planning the treatment of breast cancer.
通过葡聚糖包被活性炭分析法对170例乳腺癌患者的275份样本进行了雌激素受体(ER)检测。结果显示,ER阳性率为51.2%。女性患者的ER状态与年龄或绝经无关。AB血型患者的阳性率最低。所有血型中阳性患者的分布与日本作者报道的相似。ER阳性癌症的DNA水平相对低于阴性癌症。癌组织的病理检查表明,ER阳性癌症分化良好。ER阳性患者的3年无病生存率和4年生存率均高于阴性患者。了解ER状态有助于规划乳腺癌的治疗。