Shi Lingyan, Liu Wei, He Xuan, Wang Zihan, Xian Weiping, Wang Jie, Cui Sheng
State Key Laboratory of Materials-Oriented Chemical Engineering, College of Material Science and Engineering, Nanjing Tech University, Nanjing 211816, China.
Institute of Chemical Materials, China Academy of Engineering Physics, Mianyang 621900, China.
Anal Methods. 2024 Mar 7;16(10):1489-1495. doi: 10.1039/d3ay02052e.
High fluorescence background poses a substantial challenge to surface-enhanced Raman scattering (SERS), thereby limiting its broader applicability across diverse domains. In this work, silver nanoparticle (Ag NP)-loaded graphene oxide aerogel nanomaterials (GO-Ag ANM) were prepared for sensitive SERS detection of fluorescent explosive 2,4,8,10-tetranitrobenzo-1,3,6,6-tetraazapentaenopyridine (BPTAP) by a fluorescence quenching strategy. By harnessing the fluorescence quenching properties of graphene and the localized surface plasmon resonance of silver nanoparticles, the synthesized aerogels exhibited effective fluorescence quenching and Raman enhancement capabilities when employed for BPTAP analysis with 532 nm laser excitation. Significantly, precise control over the loading quantity of silver nanoparticles (Ag NPs) resulted in the remarkable sensitivity of the surface-enhanced Raman scattering (SERS) effect. This method allowed for the detection of fluorescent explosive BPTAP at an extraordinarily low concentration of 1 × 10 M. Furthermore, the approach also demonstrated excellent detection capabilities for the dyes R6G, CV, and RhB. This study offers valuable insights for the sensitive detection of fluorescent molecules.
高荧光背景对表面增强拉曼散射（SERS）构成了重大挑战，从而限制了其在不同领域的更广泛应用。在这项工作中，通过荧光猝灭策略制备了负载银纳米颗粒（Ag NP）的氧化石墨烯气凝胶纳米材料（GO-Ag ANM），用于对荧光炸药2,4,8,10-四硝基苯并-1,3,6,6-四氮杂戊烯并吡啶（BPTAP）进行灵敏的SERS检测。通过利用石墨烯的荧光猝灭特性和银纳米颗粒的局域表面等离子体共振，当使用532 nm激光激发进行BPTAP分析时，合成的气凝胶表现出有效的荧光猝灭和拉曼增强能力。值得注意的是，对银纳米颗粒（Ag NPs）负载量的精确控制导致了表面增强拉曼散射（SERS）效应的显著灵敏度。该方法能够在极低浓度1×10⁻⁹ M下检测荧光炸药BPTAP。此外，该方法对染料罗丹明6G（R6G）、结晶紫（CV）和罗丹明B（RhB）也表现出优异的检测能力。本研究为荧光分子的灵敏检测提供了有价值的见解。
