Mardiyan Kurniawati Eighty, Anisah Rahmawati Nur, Hardianto Gatut, Paraton Hari, Hastono Setyo Hadi Tri
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia.
Int J Reprod Biomed. 2024 Jan 25;21(12):957-974. doi: 10.18502/ijrm.v21i12.15034. eCollection 2023 Dec.
Management for pelvic floor disorders needs to be improved. Platelet-rich plasma (PRP) offers an innovative treatment in general medical care to promote cell regeneration.
This review aims to investigate the role of PRP in pelvic floor disorders.
6 international databases were accessed using several keywords namely PubMed, Science Direct, Cochrane Library, ProQuest, Google Scholar, and Scopus. The inclusion criteria were articles written in English, published in 10-yr period from 2012 until 2022, and investigated the relevant topic. This systematic review followed PRISMA guideline.
644 articles were found in several databases and 15 articles met the criteria. Management for pelvic floor disorders needs to be improved, but there are still many challenges, such as less effective treatments, risk of recurrence, and postoperative wound healing. PRP offers an innovative treatment in general medical care to promote cell regeneration. A total of 644 articles from the database were found, but 15 studies met the criteria. A total of 600 women with various pelvic floor disorders treated with PRP were analyzed. PRP positively impacts female sexual dysfunction, perineal trauma, vulvovaginal atrophy, stress urinary incontinence, vesicovaginal fistula, perineal rupture, and pelvic organ prolapse. Dosages, preparation techniques, injection techniques, and additive materials are varied. Most studies do not report side effects from the therapy, but the urinary disorder complaints must be paid attention to.
PRP can be used to manage pelvic floor disorders. Future studies should clarify and standardize the dose in each case and how to make PRP produce the best results.
盆底功能障碍的管理需要改进。富血小板血浆（PRP）在普通医疗中提供了一种促进细胞再生的创新治疗方法。
本综述旨在探讨PRP在盆底功能障碍中的作用。
使用多个关键词检索6个国际数据库，即PubMed、Science Direct、Cochrane图书馆、ProQuest、谷歌学术和Scopus。纳入标准为英文撰写、2012年至2022年10年间发表且研究相关主题的文章。本系统综述遵循PRISMA指南。
在多个数据库中检索到644篇文章，15篇文章符合标准。盆底功能障碍的管理需要改进，但仍存在许多挑战，如治疗效果不佳、复发风险和术后伤口愈合问题。PRP在普通医疗中提供了一种促进细胞再生的创新治疗方法。从数据库中总共检索到644篇文章，但15项研究符合标准。共分析了600例接受PRP治疗的各种盆底功能障碍的女性。PRP对女性性功能障碍、会阴创伤、外阴阴道萎缩、压力性尿失禁、膀胱阴道瘘、会阴裂伤和盆腔器官脱垂有积极影响。剂量、制备技术、注射技术和添加剂材料各不相同。大多数研究未报告该疗法的副作用，但必须注意泌尿系统疾病的主诉。
PRP可用于管理盆底功能障碍。未来的研究应明确并规范每种情况下的剂量以及如何使PRP产生最佳效果。
