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在蓖麻分支支架技术上运用医生改良开窗术重建主动脉弓上孤立的左椎动脉。

Utilizing physician modified fenestration on the castor branched stent technique for reconstruction of an isolated left vertebral artery on the aortic arch.

作者信息

Luo Zeng-Rong, Li Sai-Lan, Chen Liang-Wan, Huang Rong-Da

机构信息

Department of Cardiovascular Surgery, Fujian Medical University Union Hospital, Fuzhou, 350001, China.

Key Laboratory of Cardio-Thoracic Surgery (Fujian Medical University), Fuzhou, Fujian Province, China.

出版信息

Sci Rep. 2024 Feb 19;14(1):4051. doi: 10.1038/s41598-024-54781-8.

Abstract

The study aimed to provide physician modified fenestration (PMF) on a single-branched stent for the aortic arch (Castor) to protect the isolated left vertebral artery (ILVA) during thoracic endovascular aortic repair (TEVAR). Patients who underwent TEVAR involving ILVA reconstruction through PMF performing on the Castor branched stent were included in a retrospective, multi-centre study from June 2018 to December 2022. In these patients, all proximal landing zones of "Castor" were positioned in Ishimaru zone 2a. A total of twenty-five patients met the inclusion criteria and the achievement rate showed 25/25 (100%) success in them. The twenty-five patients had a median follow-up length of 28.5 ± 14.6 months. One patient (4.0%) suffered from postoperative ischemic stroke before discharge. One patient (4.0%) died from a hemodialysis-related brain hemorrhage before discharge on the 29th day after the procedure. One patient died of advanced liver cancer in the 33th month after discharge. Aortic rupture, stroke or spinal cord injury did not occur throughout the follow-up period after discharge. Two patients (8.0%) experienced endoleak at the fenestration, however, resulting in only one's necessity for reintervention. Notably, the procedure effectively maintained ILVAs patency for all patients during follow up. According to our preliminary findings, performing a TEVAR under local anaesthesia using PMF on a Castor branched stent for ILVA preservation appeared practical, secure, and effective.

摘要

该研究旨在对用于主动脉弓的单分支支架(Castor)进行医生改良开窗术(PMF),以在胸主动脉腔内修复术(TEVAR)期间保护孤立的左椎动脉(ILVA)。对2018年6月至2022年12月期间接受通过在Castor分支支架上进行PMF进行ILVA重建的TEVAR患者进行了一项回顾性多中心研究。在这些患者中,“Castor”的所有近端锚定区均位于石丸2a区。共有25例患者符合纳入标准,成功率为25/25(100%)。这25例患者的中位随访时间为28.5±14.6个月。1例患者(4.0%)在出院前发生术后缺血性卒中。1例患者(4.0%)在术后第29天出院前死于与血液透析相关的脑出血。1例患者在出院后第33个月死于晚期肝癌。出院后的整个随访期间未发生主动脉破裂、卒中或脊髓损伤。然而,2例患者(8.0%)在开窗处出现内漏,只有1例需要再次干预。值得注意的是,该手术在随访期间有效地维持了所有患者的ILVA通畅。根据我们的初步研究结果,在局部麻醉下使用PMF对Castor分支支架进行TEVAR以保留ILVA似乎是可行、安全且有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a8a/10876643/81ed7b2ac58b/41598_2024_54781_Fig1_HTML.jpg

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