Mohamed Salih Rajaa, Olusoji Rahman, Nwankwo Chizoba, Osei Noah, Kwentoh Ifeoma P, Nwankwo Obinna T
Internal Medicine, Harlem Hospital Center, New York City, USA.
Cureus. 2024 Jan 20;16(1):e52624. doi: 10.7759/cureus.52624. eCollection 2024 Jan.
Myeloid sarcoma (MS) represents a unique clinical presentation of acute myeloid leukemia (AML). This report describes a case of MS in a 66-year-old man who presented with dysphagia, nausea, vomiting, anorexia, and fatigue. Generalized lymphadenopathy was noted on physical exam and confirmed by CT scans which also showed diffuse esophageal wall thickening. Axillary lymph node biopsy was positive for MS. Bone marrow biopsy confirmed AML with 88% blasts. The patient received induction chemotherapy with decitabine and venetoclax and was planned for four cycles of treatment over three months while monitoring the response.
髓系肉瘤（MS）是急性髓系白血病（AML）的一种独特临床表现。本报告描述了一名66岁男性的MS病例，该患者出现吞咽困难、恶心、呕吐、厌食和疲劳症状。体格检查发现全身淋巴结肿大，CT扫描证实了这一情况，CT扫描还显示食管壁弥漫性增厚。腋窝淋巴结活检MS呈阳性。骨髓活检确诊为AML，原始细胞占88%。患者接受了地西他滨和维奈克拉诱导化疗，并计划在三个月内进行四个周期的治疗，同时监测反应。
