裂环-前泽泻烷型倍半萜的化学成分与药理活性
Chemical composition and pharmacological activity of seco-prezizaane-type sesquiterpenes.
作者信息
Jin Ye, Xie Yanqing, Zhang Peng, Khan Afsar, Zhou Zhihong, Liu Lu
机构信息
Yunnan Yunzhong Institute of Nutrition and Health, Yunnan University of Chinese Medicine, Kunming 650500, China.
Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
出版信息
Chin Herb Med. 2023 Dec 11;16(1):70-81. doi: 10.1016/j.chmed.2023.06.003. eCollection 2024 Jan.
The seco-prezizaane-type sesquiterpenes (SPS), as a special class of sesquiterpenes with a highly oxidative five-ring cage structure and seven consecutive chiral centers, are isolated from the genus , which have a variety of biological activities, including neurotoxicity and neurotrophic effects, etc. This review summarizes the chemical constituents and pharmacological effects of SPS, and discusses the potential trend and scope of future research.
裂环-普雷齐赞烷型倍半萜（SPS）作为一类特殊的倍半萜，具有高度氧化的五环笼状结构和七个连续的手性中心，从该属植物中分离得到，具有多种生物活性，包括神经毒性和神经营养作用等。本文综述了SPS的化学成分和药理作用，并探讨了未来研究的潜在趋势和范围。
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