Shibukawa Takeshi, Fujiyoshi Akira, Moniruzzaman Mohammad, Miyagawa Naoko, Kadota Aya, Kondo Keiko, Saito Yoshino, Kadowaki Sayaka, Hisamatsu Takashi, Yano Yuichiro, Arima Hisatomi, Tooyama Ikuo, Ueshima Hirotsugu, Miura Katsuyuki
Department of Public Health, Shiga University of Medical Science, Shiga, Japan.
Rehabilitation Units, Shiga University of Medical Science Hospital, Shiga, Japan.
Prev Med Rep. 2024 Jan 17;38:102615. doi: 10.1016/j.pmedr.2024.102615. eCollection 2024 Feb.
Increasing physical activity may prevent cognitive decline. Previous studies primarily focused on older adults and used self-reported questionnaires to assess physical activity. We examined the relationship between step count, an objective measure of physical activity, and cognitive function in community-based middle-aged and older Japanese men.
The Shiga Epidemiological Study of Subclinical Atherosclerosis randomly recruited community-dwelling healthy men aged 40-79 years from Shiga, Japan, and measured their step counts over 7 consecutive days using a pedometer at baseline (2006-2008). Among men who returned for follow-up (2009-2014), we assessed their cognitive function using the Cognitive Abilities Screening Instrument (CASI) score. We restricted our analyses to those with valid 7-day average step counts at baseline and those who remained free of stroke at follow-up (n = 676). Using analysis of covariance, we calculated the adjusted means of the CASI score according to the quartiles of the average step counts.
The mean (standard deviation) of age and unadjusted CASI score were 63.8 (9.1) years and 90.8 (5.8), respectively. The CASI score was elevated in higher quartiles of step counts (90.2, 90.4, 90.6, and 91.8 from the lowest to the highest quartile, respectively, [p for trend = 0.004]) in a model adjusted for age and education. Further adjustment for smoking, drinking, and other cardiovascular risk factors resulted in a similar pattern of association (p for trend = 0.005).
In apparently healthy middle-aged and older Japanese men, a greater 7-day average step count at baseline was associated with significantly higher cognitive function score.
增加身体活动可能预防认知功能衰退。既往研究主要聚焦于老年人，并使用自我报告问卷来评估身体活动。我们研究了步数（一种身体活动的客观测量指标）与日本社区中老年男性认知功能之间的关系。
滋贺亚临床动脉粥样硬化流行病学研究从日本滋贺随机招募了40 - 79岁的社区居住健康男性，并在基线期（2006 - 2008年）使用计步器连续7天测量他们的步数。在返回接受随访的男性（2009 - 2014年）中，我们使用认知能力筛查工具（CASI）评分评估他们的认知功能。我们将分析限制在基线期有有效7天平均步数且随访时仍无中风的人群（n = 676）。使用协方差分析，我们根据平均步数的四分位数计算了CASI评分的调整均值。
年龄的均值（标准差）和未调整的CASI评分分别为63.8（9.1）岁和90.8（5.8）。在调整了年龄和教育程度的模型中，步数较高四分位数组的CASI评分升高（从最低到最高四分位数分别为90.2、90.4、90.6和91.8，[趋势p值 = 0.004]）。进一步调整吸烟、饮酒和其他心血管危险因素后，得到了相似的关联模式（趋势p值 = 0.005）。
在表面健康的日本中老年男性中，基线期7天平均步数越多与认知功能评分显著越高相关。
